Evidence map›Paper›PMID 24750703›Full record

ArticleThe neuroradiology journal2014

Neuroradiology and histopathology in two cases of adult medulloblastoma.

Alfredo E Romero-Rojas, Julio A Diaz-Perez, Sharat Raju, Alfonso Lozano-Castillo

Open access · greenAbstract readCase Reports
In one paragraph

Article in The neuroradiology journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Alfredo E Romero-RojasDepartment of Neurosurgery, National Institute of Cancer; Bogota, Colombia - jdiazperez@ucsd.edu.
Julio A Diaz-PerezMoores Cancer Center, University of California; San Diego, La Jolla, CA, USA - Department of Pathology, University of Santander; Bucaramanga, Colombia.
Sharat RajuMoores Cancer Center, University of California; San Diego, La Jolla, CA, USA.
Alfonso Lozano-CastilloDepartment of Neurosurgery, National Institute of Cancer; Bogota, Colombia.
Instituto Nacional de Cancerología · COMoores Cancer Center

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medulloblastoma (MB) is the most common central nervous system neoplasm in children and only rarely presents in the adult population. Recent molecular biology findings have characterized MB as a heterogeneous neoplasm distinguished by well-defined tumour subsets each with specific histologic and molecular features. Available immunohistochemical stains can now be used to differentiate the distinct molecular types of MB. This report analyzed the histopathologic and neuroradiologic features of two new cases of adult MB. Imaging studies in these patients revealed the morphological appearance of high-grade, well-circumscribed heterogeneous tumours with necrosis, located laterally within the posterior cranial fossa. Histopathology of resected samples demonstrated high-grade tumours (WHO grade IV) containing sheets of undifferentiated neural cells with high mitotic activity and evidence of necrosis. The histopathologic and molecular characteristics of these cases of MB are reviewed for potential applications in new molecular methods of imaging.

Indexed as

BiopsyCerebellar NeoplasmsDiagnosis, DifferentialFemaleHumansMagnetic Resonance ImagingMedulloblastomaMiddle AgedTomography, X-Ray Computedadult patientshistopathologyimmunohistochemistrymedulloblastomamolecular imagingneuroradiology

Identifiers

PMID24750703
PMCPMC4202854
OpenAlexW2106980542

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.