ArticleJournal of evolutionary biology2014
Evidence of trade-offs shaping virulence evolution in an emerging wildlife pathogen.
Article in Journal of evolutionary biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed.
- Infected host competence overshadows heterogeneity in susceptibility in shaping experimental epizootics.Ecology · 2026Article
- Infected host competence overshadows heterogeneity in susceptibility in shaping experimental epizootics.bioRxiv : the preprint server for biology · 2025Article
- Pathogen priming alters host transmission potential and predictors of transmissibility in a wild songbird species.mSphere · 2025Article
- Host Disease Tolerance Predicts Transmission Probability for a Songbird Pathogen.Ecology and evolution · 2025Article
- Pathogen priming alters host transmission potential and predictors of transmissibility in a wild songbird species.bioRxiv : the preprint server for biology · 2024Article
- Prior exposure to pathogens augments host heterogeneity in susceptibility and has key epidemiological consequences.PLoS pathogens · 2024Article
- Prior exposure to pathogens augments host heterogeneity in susceptibility and has key epidemiological consequences.bioRxiv : the preprint server for biology · 2024Article
- Wildlife-Livestock Host Community Maintains Simultaneous Epidemiologic Cycles ofVeterinary sciences · 2024Article
- High virulence is associated with pathogen spreadability in a songbird-bacterial system.Royal Society open science · 2023Article
- Disease tolerance alters host competence in a wild songbird.Biology letters · 2021Article
- Host population dynamics in the face of an evolving pathogen.The Journal of animal ecology · 2021Article
- Virus shedding kinetics and unconventional virulence tradeoffs.PLoS pathogens · 2021Article
- Treating symptomatic infections and the co-evolution of virulence and drug resistance.Peer community journal · 2021Article
- Experimental evidence for stabilizing selection on virulence in a bacterial pathogen.Evolution letters · 2020Article
- Host exposure history modulates the within-host advantage of virulence in a songbird-bacterium system.Scientific reports · 2019Article
- Feeder density enhances house finch disease transmission in experimental epidemics.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Article
- Life-history correlations change under coinfection leading to higher pathogen load.Evolution letters · 2018Article
- Incomplete host immunity favors the evolution of virulence in an emergent pathogen.Science (New York, N.Y.) · 2018Article
- Differing House Finch Cytokine Expression Responses to Original and Evolved Isolates ofFrontiers in immunology · 2018Article
- Systematic detection of positive selection in the human-pathogen interactome and lasting effects on infectious disease susceptibility.PloS one · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
In the mid-1990s, the common poultry pathogen Mycoplasma gallisepticum (MG) made a successful species jump to the eastern North American house finch Haemorhous mexicanus (HM). Subsequent strain diversification allows us to directly quantify, in an experimental setting, the transmission dynamics of three sequentially emergent geographic isolates of MG, which differ in the levels of pathogen load they induce. We find significant among-strain variation in rates of transmission as well as recovery. Pathogen strains also differ in their induction of host morbidity, measured as the severity of eye lesions due to infection. Relationships between pathogen traits are also investigated, with transmission and recovery rates being significantly negatively correlated, whereas transmission and virulence, measured as average eye lesion score over the course of infection, are positively correlated. By quantifying these disease-relevant parameters and their relationships, we provide the first analysis of the trade-offs that shape the evolution of this important emerging pathogen.
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