Evidence map›Paper›PMID 24749000›Full record

ArticleAdvances in bioscience and biotechnology (Print)2013

Evaluation of HemogloBind™ treatment for preparation of samples for cholinesterase analysis.

Kevin G McGarry, Ryan A Bartlett, Nicholas J Machesky, Thomas H Snider, Robert A Moyer, David T Yeung, Matthew K Brittain

Open access · diamondAbstract read
In one paragraph

Article in Advances in bioscience and biotechnology (Print), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kevin G McGarryBattelle Biomedical Research Center, Battelle Memorial Institute, Columbus, USA.
Ryan A BartlettBattelle Biomedical Research Center, Battelle Memorial Institute, Columbus, USA.
Nicholas J MacheskyBattelle Biomedical Research Center, Battelle Memorial Institute, Columbus, USA.
Thomas H SniderBattelle Biomedical Research Center, Battelle Memorial Institute, Columbus, USA.
Robert A MoyerBattelle Biomedical Research Center, Battelle Memorial Institute, Columbus, USA.
David T YeungNational Institutes of Health/National Institute of Neurological Disorders and Stroke, Bethesda, USA.
Matthew K BrittainBattelle Biomedical Research Center, Battelle Memorial Institute, Columbus, USA.
Battelle · USNational Institute of Neurological Disorders and Stroke · US

Funding

Intramural NIH HHS Z99 NS999999
6 · The paper itself

Abstract

Acetylcholine is an essential neurotransmitter found throughout the nervous system. Its action on postsynaptic receptors is regulated through hydrolysis by various carboxylesterases, especially cholinesterases (ChEs). The acute toxicity of organophosphate (OP) compounds is directly linked to their action as inhibitors of ChE. One widely used assay for evaluating ChE activity is a spectrophotometric method developed by Ellman

Indexed as

AcetylcholinesteraseCholinesteraseHemoglobinHemogloBind™Sample Preparation

Identifiers

PMID24749000
PMCPMC3989896
OpenAlexW1971523422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.