Evidence map›Paper›PMID 24748942›Full record

ArticleThe Korean journal of pain2014

Epidural Infusion of Morphine and Levobupivacaine through a Subcutaneous Port for Cancer Pain Management.

Bong Ha Heo, Tae Hee Pyeon, Hyung Gon Lee, Woong Mo Kim, Jeong Il Choi, Myung Ha Yoon

Open access · diamondAbstract read
In one paragraph

Article in The Korean journal of pain, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Bong Ha HeoDepartment of Anesthesiology and Pain Medicine, Chonnam National University Medical School, Gwangju, Korea.
Tae Hee PyeonDepartment of Anesthesiology and Pain Medicine, Chonnam National University Medical School, Gwangju, Korea.
Hyung Gon LeeDepartment of Anesthesiology and Pain Medicine, Chonnam National University Medical School, Gwangju, Korea.
Woong Mo KimDepartment of Anesthesiology and Pain Medicine, Chonnam National University Medical School, Gwangju, Korea.
Jeong Il ChoiDepartment of Anesthesiology and Pain Medicine, Chonnam National University Medical School, Gwangju, Korea.
Myung Ha YoonDepartment of Anesthesiology and Pain Medicine, Chonnam National University Medical School, Gwangju, Korea.
Chonnam National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo manage intractable cancer pain, an alternative to systemic analgesics is neuraxial analgesia. In long-term treatment, intrathecal administration could provide a more satisfactory pain relief with lower doses of analgesics and fewer side-effects than that of epidural administration. However, implantable drug delivery systems using intrathecal pumps in Korea are very expensive. Considering cost-effectiveness, we performed epidural analgesia as an alternative to intrathecal analgesia.

methodsWe retrospectively investigated the efficacy, side effects, and complications of epidural morphine and local anesthetic administration through epidural catheters connected to a subcutaneous injection port in 29 Korean terminal cancer patients. Patient demographic data, the duration of epidural administration, preoperative numerical pain rating scales (NRS), side effects and complications related to the epidural catheterization and the drugs, and the numerical pain rating scales on the 1st, 3rd, 7th and 30th postoperative days were determined from the medical records.

resultsThe average score for the numerical pain rating scales for the 29 patients decreased from 7 ± 1.0 at baseline to 3.6 ± 1.4 on postoperative day 1 (P < 0.001). A similar decrease in pain intensity was maintained for 30 days (P < 0.001). Nausea and vomiting were the most frequently reported side effects of the epidural analgesia and two patients (6.9%) experienced paresthesia.

conclusionsEpidural morphine and local anesthetic infusion with a subcutaneous pump seems to have an acceptable risk-benefit ratio and allows a high degree of autonomy to patients with cancer pain.

Indexed as

cancer painefficacyepidural catheterportside effects

Identifiers

PMID24748942
PMCPMC3990822
OpenAlexW2129279645

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.