ArticleWorld journal of diabetes2014
Gas-forming liver abscess associated with rapid hemolysis in a diabetic patient.
Article in World journal of diabetes, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 23 citations in OpenAlex.
- Pneumoperitoneum Caused by a Ruptured Splenic Abscess Mimicking Gastrointestinal Perforation: A Case Report.Surgical case reports · 2025Article
- Harnessing Prebiotics to Improve Type 2 Diabetes Outcomes.Nutrients · 2024Review
- Survival in a Case of Emphysematous Cholecystitis With Sepsis Caused by Clostridium perfringens.Cureus · 2023Article
- Liver abscess caused by Clostridium perfringens after left hepatic trisectionectomy for perihilar cholangiocarcinoma: a case report.Surgical case reports · 2023Article
- Antimicrobial potential of myricetin-coated zinc oxide nanocomposite against drug-resistant Clostridium perfringens.BMC microbiology · 2023Article
- Article
- A case of severe intravascular haemolysis.EJHaem · 2022Article
- Clostridium perfringens and Escherichia coli Bacteremia in a Patient with Acute Obstructive Suppurative Cholangitis: A Case Report and Review of the Literature.The American journal of case reports · 2022Review
- Clostridium perfringens sepsis after pancreatoduodenectomy: a case report.Surgical case reports · 2022Article
- Article
- Fatal Clostridium perfringens sepsis with spleen rupture and intraabdominal massive bleeding in a 37-week pregnancy.IDCases · 2021Article
- Clostridium perfringens epsilon toxin binds to erythrocyte MAL receptors and triggers phosphatidylserine exposure.Journal of cellular and molecular medicine · 2020Article
- Type A fulminant Clostridium perfringens sepsis indicated RBC/Hb discrepancy; a case report.BMC infectious diseases · 2019Article
- Clostridium paraputrificum septicemia and liver abscess.World journal of hepatology · 2018Article
- Massive intravascular haemolysis due toBMJ case reports · 2018Article
- Clostridium perfringens α-toxin impairs erythropoiesis by inhibition of erythroid differentiation.Scientific reports · 2017Article
- Massive haemolysis, gas-forming liver abscess and sepsis due to Clostridium perfringens bacteraemia.BMJ case reports · 2016Article
- Hepatic abscess-associated Clostridial bacteraemia presenting with intravascular haemolysis and severe hypertension.BMJ case reports · 2016Article
- Gas-Forming Pyogenic Liver Abscess with Septic Shock.Case reports in critical care · 2015Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We experienced a case of liver abscess due to Clostridium perfringens (CP) complicated with massive hemolysis and rapid death in an adequately controlled type 2 diabetic patient. The patient died 6 h after his first visit to the hospital. CP was later detected in a blood culture. We searched for case reports of CP septicemia and found 124 cases. Fifty patients survived, and 74 died. Of the 30 patients with liver abscess, only 3 cases survived following treatment with emergency surgical drainage. For the early detection of CP infection, detection of Gram-positive rods in the blood or drainage fluid is important. Spherocytes and ghost cells indicate intravascular hemolysis. The prognosis is very poor once massive hemolysis occurs. The major causative organisms of gas-forming liver abscess in diabetic patients are Klebsiella pneumoniae (K. pneumoniae) and Escherichia coli (E. coli). Although CP is relatively rare, the survival rate is very poor compared with those of K. pneumoniae and E. coli. Therefore, for every case that presents with a gas-forming liver abscess, the possibility of CP should be considered, and immediate aspiration of the abscess and Gram staining are important.
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