Evidence map›Paper›PMID 24748840›Full record

ArticleJournal of ginseng research2014

Processed Vietnamese ginseng: Preliminary results in chemistry and biological activity.

Thi Hong Van Le, Seo Young Lee, Tae Ryong Kim, Jae Young Kim, Sung Won Kwon, Ngoc Khoi Nguyen, Jeong Hill Park, Minh Duc Nguyen

Abstract read
In one paragraph

Article in Journal of ginseng research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Novel indole alkaloids from the flower buds ofJournal of ginseng research · 2026
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  2. Nephroprotective Effect of BlackMolecules (Basel, Switzerland) · 2026
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  13. Increase in Protective Effect ofMolecules (Basel, Switzerland) · 2019
    Article
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Thi Hong Van LeSchool of Pharmacy, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam.
Seo Young LeeResearch Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea.
Tae Ryong KimResearch Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea.
Jae Young KimResearch Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea.
Sung Won KwonResearch Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea.
Ngoc Khoi NguyenSchool of Pharmacy, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam.
Jeong Hill ParkResearch Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea.
Minh Duc NguyenSchool of Pharmacy, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study was carried out to investigate the effect of the steaming process on chemical constituents, free radical scavenging activity, and antiproliferative effect of Vietnamese ginseng.

methodsSamples of powdered Vietnamese ginseng were steamed at 120°C for various times and their extracts were subjected to chemical and biological studies.

resultsUpon steaming, contents of polar ginsenosides, such as Rb1, Rc, Rd, Re, and Rg1, were rapidly decreased, whereas less polar ginsenosides such as Rg3, Rg5, Rk1, Rk3, and Rh4 were increased as reported previously. However, ocotillol type saponins, which have no glycosyl moiety at the C-20 position, were relatively stable on steaming. The radical scavenging activity was increased continuously up to 20 h of steaming. Similarly, the antiproliferative activity against A549 lung cancer cells was also increased.

conclusionIt seems that the antiproliferative activity is closely related to the contents of ginsenoside Rg3, Rg5, and Rk1.

Indexed as

antiproliferationginsenosidePanax vietnamensissteamingVietnamese ginseng

Identifiers

PMID24748840
PMCPMC3986633

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.