Evidence map›Paper›PMID 24748784›Full record

SynthesisClinical interventions in aging2014

Physical activity and cognitive function in individuals over 60 years of age: a systematic review.

Ashley Carvalho, Irene Maeve Rea, Tanyalak Parimon, Barry J Cusack

Registry-linked trialAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Clinical interventions in aging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05904171 (Cognitive, Affective, and Motor Effects of Tangotherapy in Parkinson's Disease), which is not on this map. Cited by 111 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05904171 nacompletednot on this mapstarted 2023, after this paper: background citation

Cognitive, Affective, and Motor Effects of Tangotherapy in Parkinson's Disease

TypeinterventionalSponsorIstituto Auxologico ItalianoRan2023 to 2025Enrolled45ConditionsParkinson DiseaseArmsTangotherapy, Physical activity
3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ashley CarvalhoDepartment of Public Health, Queen's University Belfast, Northern Ireland, UK ; School of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Northern Ireland, UK.
Irene Maeve ReaSchool of Medicine, Dentistry and Biomedical Science, Queen's University Belfast, Northern Ireland, UK.
Tanyalak ParimonResearch and Development Service, Veterans Affairs Medical Center, Boise, ID, USA ; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington, Seattle, WA, USA.
Barry J CusackResearch and Development Service, Veterans Affairs Medical Center, Boise, ID, USA ; Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington, Seattle, WA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is unclear whether physical activity in later life is beneficial for maintenance of cognitive function. We performed a systematic review examining the effects of exercise on cognitive function in older individuals, and present possible mechanisms whereby physical activity may improve cognition.

methodsSources consisted of PubMed, Medline, CINAHL, the Cochrane Controlled Trials Register, and the University of Washington, School of Medicine Library Database, with a search conducted on August 15, 2012 for publications limited to the English language starting January 1, 2000. Randomized controlled trials including at least 30 participants and lasting at least 6 months, and all observational studies including a minimum of 100 participants for one year, were evaluated. All subjects included were at least 60 years of age.

resultsTwenty-seven studies met the inclusion criteria. Twenty-six studies reported a positive correlation between physical activity and maintenance or enhancement of cognitive function. Five studies reported a dose-response relationship between physical activity and cognition. One study showed a nonsignificant correlation.

conclusionThe preponderance of evidence suggests that physical activity is beneficial for cognitive function in the elderly. However, the majority of the evidence is of medium quality with a moderate risk of bias. Larger randomized controlled trials are needed to clarify the association between exercise and cognitive function and to determine which types of exercise have the greatest benefit on specific cognitive domains. Despite these caveats, the current evidence suggests that physical activity may help to improve cognitive function and, consequently, delay the progression of cognitive impairment in the elderly.

Indexed as

AgedCognitionCognition DisordersExercise TherapyHumansMiddle AgedMotor Activitycognitive functionelderlyexercise

Identifiers

PMID24748784
PMCPMC3990369

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.