Evidence map›Paper›PMID 24748421›Full record

ReviewJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2014

Is regenerative medicine a new hope for kidney replacement?

Maciej Nowacki, Tomasz Kloskowski, Marta Pokrywczyńska, Łukasz Nazarewski, Arkadiusz Jundziłł, Katarzyna Pietkun, Dominik Tyloch, Marta Rasmus, Karolina Warda, Samy L Habib and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Stem Cell Aging and Regenerative Medicine.Advances in experimental medicine and biology · 2021
    Review
  3. Article
  4. Advances in the Knowledge about Kidney Decellularization and Repopulation.Frontiers in bioengineering and biotechnology · 2017
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maciej NowackiDepartment of Tissue Engineering, Nicolaus Copernicus University in Toruń, Ludwik Rydygier Collegium Medicum, Ul. Karłowicza 24, 85-092, Bydgoszcz, Poland, maciej.s.nowacki@gmail.com.
Tomasz Kloskowski
Marta Pokrywczyńska
Łukasz Nazarewski
Arkadiusz Jundziłł
Katarzyna Pietkun
Dominik Tyloch
Marta Rasmus
Karolina Warda
Samy L Habib
Tomasz Drewa

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The availability of kidney and other organs from matching donors is not enough for many patients on demand for organ transplant. Unfortunately, this situation is not better despite the many of new interesting projects of promoting family, cross or domino transplants. These inexorable global statistics forced medical researchers to find a new potential therapeutic option that would guarantee safety and efficacy for the treatment of ESRD comparable to kidney transplantation. The aim of our review is to summarize the scientific literature that relating to the modern as well as innovative experimental methods and possibilities of kidney regeneration and, in addition, to find whether the regenerative medicine field will be a new hope for curing the patient with renal disease complications. The most important achievements in the field of regenerative medicine of kidney, which were mentioned and described here, are currently cumulated in 4 areas of interest: stem cell-based therapies, neo-kidneys with specially designed scaffolds or cell-seeded matrices, bioartificial kidneys and innovative nanotechnologically bioengineered solutions. Nowadays, we can add some remarks that the regenerative medicine is still insufficient to completely replace current therapy methods used in patients with chronic kidney disease especially with the end-stage renal disease where in many cases kidney transplantation is the only one chance. But we think that development of regenerative medicine especially in the last 20 years brings us more and more closer to solve many of today's problems at the frontier of nephrology and transplantology.

Indexed as

Bioartificial OrgansHumansKidney Failure, ChronicKidney TransplantationRegenerative MedicineStem Cell TransplantationTissue Engineering

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.