Evidence map›Paper›PMID 24748033›Full record

ArticlePloS one2014

Stability of the associations between early life risk indicators and adolescent overweight over the evolving obesity epidemic.

Lise Graversen, Thorkild I A Sørensen, Liselotte Petersen, Ulla Sovio, Marika Kaakinen, Annelli Sandbæk, Jaana Laitinen, Anja Taanila, Anneli Pouta, Marjo-Riitta Järvelin and 1 more

Abstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lise GraversenSection for General Medical Practice, Department of Public Health, Aarhus University, Aarhus, Denmark.
Thorkild I A SørensenInstitute of Preventive Medicine, Bispebjerg and Frederiksberg University Hospital, The Capital Region, Copenhagen, Denmark; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Liselotte PetersenNational Centre for Register-Based Research, Faculty of Social Sciences, Aarhus University, Aarhus, Denmark.
Ulla SovioDepartment of Obstetrics and Gynaecology, University of Cambridge, Cambridge, United Kingdom; Department of Epidemiology and Biostatistics, Imperial College, London, United Kingdom.
Marika KaakinenDepartment of Epidemiology and Biostatistics, Imperial College, London, United Kingdom; Institute of Health Sciences, University of Oulu, Oulu, Finland; Biocenter Oulu, University of Oulu, Oulu, Finland.
Annelli SandbækSection for General Medical Practice, Department of Public Health, Aarhus University, Aarhus, Denmark.
Jaana LaitinenFinnish Institute of Occupational Health, Oulu, Finland.
Anja TaanilaInstitute of Health Sciences, University of Oulu, Oulu, Finland; Primary Health Care Unit, University Hospital of Oulu, Oulu, Finland.
Anneli PoutaNational Institute of Health and Welfare, Oulu, Finland; Department of Obstetrics and Gynecology, University of Oulu and Oulu University Hospital, Oulu, Finland.
Marjo-Riitta JärvelinDepartment of Epidemiology and Biostatistics, Imperial College, London, United Kingdom; Institute of Health Sciences, University of Oulu, Oulu, Finland; Biocenter Oulu, University of Oulu, Oulu, Finland; Primary Health Care Unit, University Hospital of Oulu, Oulu, Finland; National Institute of Health and Welfare, Oulu, Finland.
Carsten ObelSection for General Medical Practice, Department of Public Health, Aarhus University, Aarhus, Denmark.

Funding

Medical Research Council G0500539Medical Research Council G0600705Medical Research Council PS0476NCHHSTP CDC HHS U22 PS000476
6 · The paper itself

Abstract

backgroundPre- and perinatal factors and preschool body size may help identify children developing overweight, but these factors might have changed during the development of the obesity epidemic.

objectiveWe aimed to assess the associations between early life risk indicators and overweight at the age of 9 and 15 years at different stages of the obesity epidemic.

methodsWe used two population-based Northern Finland Birth Cohorts including 4111 children born in 1966 (NFBC1966) and 5414 children born in 1985-1986 (NFBC1986). In both cohorts, we used the same a priori defined prenatal factors, maternal body mass index (BMI), birth weight, infant weight (age 5 months and 1 year), and preschool BMI (age 2-5 years). We used internal references in early childhood to define percentiles of body size (<50, 50-75, 75-90 and >90) and generalized linear models to study the association with overweight, according to the International Obesity Taskforce (IOTF) definitions, at the ages of 9 and 15 years.

resultsThe prevalence of overweight at the age of 15 was 9% for children born in 1966 and 16% for children born in 1986. However, medians of infant weight and preschool BMI changed little between the cohorts, and we found similar associations between maternal BMI, infant weight, preschool BMI, and later overweight in the two cohorts. At 5 years, children above the 90th percentile had approximately a 12 times higher risk of being overweight at the age of 15 years compared to children below the 50th percentile in both cohorts.

conclusionsThe associations between early body size and adolescent overweight showed remarkable stability, despite the increase in prevalence of overweight over the 20 years between the cohorts. Using consequently defined internal percentiles may be a valuable tool in clinical practice.

Indexed as

AdolescentChildFinlandHumansObesityOverweightRisk Factors

Identifiers

PMID24748033
PMCPMC3991687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.