ReviewCurrent opinion in virology2014
Polyomavirus miRNAs: the beginning.
Review in Current opinion in virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- Review
- Natural killer cells and their exosomes in viral infections and related therapeutic approaches: where are we?Cell communication and signaling : CCS · 2023Review
- Shaping the host cell environment with viral noncoding RNAs.Seminars in cell & developmental biology · 2023Review
- Article
- SV40 miR-S1 and Cellular miR-1266 Sequester Each Other from Their Targets, Enhancing Telomerase Activity and Viral Replication.Non-coding RNA · 2022Article
- Evidence of the Mechanism by Which Polyomaviruses Exploit the Extracellular Vesicle Delivery System during Infection.Viruses · 2020Review
- Liquid Biopsy to Detect DNA/RNA Based Markers of Small DNA Oncogenic Viruses for Prostate Cancer Diagnosis, Prognosis, and Prediction.Frontiers in oncology · 2020Article
- Article
- Epigenetic Regulation of Viral Biological Processes.Viruses · 2017Review
- Detection of JCPyV microRNA in blood and urine samples of multiple sclerosis patients under natalizumab therapy.Journal of neurovirology · 2015Article
- A Comprehensive Analysis of Replicating Merkel Cell Polyomavirus Genomes Delineates the Viral Transcription Program and Suggests a Role for mcv-miR-M1 in Episomal Persistence.PLoS pathogens · 2015Article
- Article
- Naturally arising strains of polyomaviruses with severely attenuated microRNA expression.Journal of virology · 2014Article
- A mouse polyomavirus-encoded microRNA targets the cellular apoptosis pathway through Smad2 inhibition.Virology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Polyomaviruses are small, double stranded DNA viruses that replicate in the nucleus of the infected cell. Since 2005, clear evidence for miRNAs has been presented for a subset of the members of this viral family, each of which express a single miRNA. All the miRNAs share in common the ability to regulate expression of the major viral regulatory protein, large T antigen. Growing evidence suggests that the major role of the miRNA is to control viral replication. In vitro studies suggesting an immmunomodulatory role for the miRNA have not been supported by in vivo infections. Very little is known about cellular targets of the viral miRNAs, however. Thus, much remains to be learned about these interesting non-coding RNAs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.