ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2014
Activation deficit correlates with weakness in chronic stroke: evidence from evoked and voluntary EMG recordings.
Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 42 citations in OpenAlex.
- Trial
- Trial
- Voluntary activation of the ankle plantar flexors: A systematic review and meta-analysis.JSAMS plus · 2025Review
- The Effects of Transcranial Direct Current Stimulation During Extended Reality Exercises for Cortical, Neuromuscular, and Clinical Recovery of Stroke Survivors.Neural plasticity · 2025Article
- User-centered development of a personalized adaptive mirror therapy for upper-limb post-stroke rehabilitation using virtual reality and myoelectric control.Frontiers in bioengineering and biotechnology · 2025Article
- Article
- Location In Vivo of the Innervation Zone in the Human Medial Gastrocnemius Using Imposed Contractions: A Comparison of the Usefulness of the M-Wave and H-Reflex.Journal of functional morphology and kinesiology · 2022Article
- Observational
- Central activation deficits contribute to post stroke lingual weakness in a rat model.Journal of applied physiology (Bethesda, Md. : 1985) · 2021Article
- Reliability of Tibialis Anterior Muscle Voluntary Activation Using the Interpolated Twitch Technique and the Central Activation Ratio in People with Stroke.Brain sciences · 2021Article
- Muscle Fiber Diameter and Density Alterations after Stroke Examined by Single-Fiber EMG.Neural plasticity · 2021Article
- Global Innervation Zone Identification With High-Density Surface Electromyography.IEEE transactions on bio-medical engineering · 2020Article
- Short-Step Adjustment and Proximal Compensatory Strategies Adopted by Stroke Survivors With Knee Extensor Spasticity for Obstacle Crossing.Frontiers in bioengineering and biotechnology · 2020Article
- Central Drive to the Paretic Ankle Plantarflexors Affects the Relationship Between Propulsion and Walking Speed After Stroke.Journal of neurologic physical therapy : JNPT · 2020Article
- A Preliminary Study of Effects of Channel Number and Location on the Repeatability of Motor Unit Number Index (MUNIX).Frontiers in neurology · 2020Article
- "It's All Sort of Cool and Interesting…but What Do I Do With It?" A Qualitative Study of Stroke Survivors' Perceptions of Surface Electromyography.Frontiers in neurology · 2020Article
- Spasticity Assessment Based on the Maximum Isometrics Voluntary Contraction of Upper Limb Muscles in Post-stroke Hemiplegia.Frontiers in neurology · 2019Article
- Spasticity may obscure motor learning ability after stroke.Journal of neurophysiology · 2018Article
- Improving the repeatability of Motor Unit Number Index (MUNIX) by introducing additional epochs at low contraction levels.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2017Article
- Imaging three-dimensional innervation zone distribution in muscles from M-wave recordings.Journal of neural engineering · 2017Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveTo use evoked (M-wave) and voluntary (during maximal voluntary contraction (MVC)) EMG recordings to estimate the voluntary activation level in chronic stroke.
methodsNine chronic hemiparetic stroke subjects participated in the experiment. M-wave (EMGM-wave) and MVC (EMGMVC) EMG values of the biceps brachii muscles were recorded.
resultsPeak torque was significantly smaller on the impaired than non-impaired side. EMGM-wave was also significantly smaller on the impaired than non-impaired side. However, the normalized EMGM-wave/TorqueMVC ratio was not significantly different between two sides. In contrast, both absolute EMGMVC and normalized EMGMVC/TorqueMVC were smaller on the impaired than non-impaired side. The voluntary activation level, EMGMVC/M-wave, was also smaller on the impaired than non-impaired side. The voluntary activation level on the impaired side was highly correlated with weakness (R=0.72), but very low (R=0.32) on the non-impaired side.
conclusionCollectively, our findings suggest that both peripheral and central factors contribute to post-stroke weakness, but activation deficit correlates most closely with weakness as estimated from maximum voluntary torque generation. SIGNIFICANCE: These findings serve to highlight the potential benefit from high-intensity exercises to enhance central activation for facilitation of motor recovery.
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