ArticlePsychiatry research2014
Orbitofrontal cortex volume and intrinsic religiosity in non-clinical psychosis.
Article in Psychiatry research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Current Understanding of Religion, Spirituality, and Their Neurobiological Correlates.Harvard review of psychiatryPooled it
- Attachment style and its impact on connection to God in individuals with brain injury: behavioral and lesion-based findings.Frontiers in neurology · 2025Article
- Religiosity and Attitudes towards Health, Disease, Death and the Use of Stimulants among Jehovah's Witnesses.International journal of environmental research and public health · 2021Article
- Religiosity and Psychotic Ideation in Stable Schizophrenia: A Role for Empathic Perspective-Taking.Behavioral sciences (Basel, Switzerland) · 2020Article
- The relationship between individual differences in gray matter volume and religiosity and mystical experiences: A preregistered voxel-based morphometry study.The European journal of neuroscience · 2020Article
- Implications of religious and spiritual practices for youth at clinical high risk for psychosis.Schizophrenia research · 2019Article
- MRI Indices of Cortical Development in Young People With Psychotic Experiences: Influence of Genetic Risk and Persistence of Symptoms.Schizophrenia bulletin · 2019Article
- Neuroanatomical correlates of familial risk-for-depression and religiosity/spirituality.Spirituality in clinical practice (Washington, D.C.) · 2017Article
- The Structure and Measurement of Unusual Sensory Experiences in Different Modalities: The Multi-Modality Unusual Sensory Experiences Questionnaire (MUSEQ).Frontiers in psychology · 2017Article
- Examining the Psychosis Continuum.Current behavioral neuroscience reports · 2015Article
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Authors and funding
8 authors.
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Abstract
Research indicates that religiosity plays a complex role in mental illness. Despite this link, little work has been done to clarify the role of religiosity in persons exhibiting non-clinical psychosis (NCP, individuals experiencing fleeting psychotic-like symptoms in the absence of a formal psychotic disorder). Further, there are no NCP investigations into whether abnormalities exist in brain structures that are associated with religiosity. Understanding these relationships in NCP is important to clarify the role of religiosity and brain structural anomalies in psychosis. Twenty individuals experiencing NCP and twenty controls were assessed for intrinsic religiosity (IR; motivation/commitment to religious beliefs and/or practices) using a well-validated self-report scale. Structural magnetic resonance imaging was used to determine volumes of the orbitofrontal cortex (OFC), a critical region that has been associated with increased religiosity. Results indicate that IR is elevated in the NCP group, and that these individuals exhibit bilateral volume reduction in both the lateral and medial OFC. Sample-wide correlations are non-significant, but show notable relationships between smaller OFC regions and increased IR. Significant negative relationships were found between OFC volume and depressive and negative symptoms. Overall, results suggest that brain abnormalities associated with NCP may also confer a heightened susceptibility for religiosity.
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