ArticleJournal of psychosomatic research2014
Early-treatment weight loss predicts 6-month weight loss in women with obesity and depression: implications for stepped care.
Article in Journal of psychosomatic research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 20 citations in OpenAlex.
- Anti-obesity medication for weight loss in early nonresponders to behavioral treatment: a randomized controlled trial.Nature medicine · 2025Trial
- An Adaptive Behavioral Intervention for Weight Loss Management: A Randomized Clinical Trial.JAMA · 2024Trial
- Getting a head start: identifying pretreatment correlates associated with early weight loss for individuals participating in weight loss treatment.Translational behavioral medicine · 2021Trial
- Planned care for obesity and cardiovascular risk reduction using a stepped-down approach: A randomized-controlled trial.Preventive medicine · 2018Trial
- Importance of early weight loss and other predictors of lower weight loss in a commercial program: A secondary data analysis.Obesity science & practice · 2024Article
- An Explainable Artificial Intelligence Software Tool for Weight Management Experts (PRIMO): Mixed Methods Study.Journal of medical Internet research · 2023Article
- A very low-carbohydrate diabetes prevention program for veterans with prediabetes: a single-arm mixed methods pilot study.Frontiers in nutrition · 2023Article
- Impact of a Novel Diabetes Prevention Intervention for Early Slow Weight Loss Responders Among Adults With Prediabetes: An Adaptive Trial.Diabetes care · 2022Article
- Developing weight navigation program to support personalized and effective obesity management in primary care settings: protocol for a quality improvement program with an embedded single-arm pilot study.Primary health care research & development · 2022Article
- Impact of the COVID-19 pandemic on initial weight loss in a digital weight management program: A natural experiment.Obesity (Silver Spring, Md.) · 2021Article
- A Pragmatic Approach to Translating Low- and Very Low-Carbohydrate Diets Into Clinical Practice for Patients With Obesity and Type 2 Diabetes.Frontiers in nutrition · 2021Article
- Noninferiority and equivalence tests in sequential, multiple assignment, randomized trials (SMARTs).Psychological methods · 2020Article
- SMART: Study protocol for a sequential multiple assignment randomized controlled trial to optimize weight loss management.Contemporary clinical trials · 2019Article
- Article
- Early weight loss predicts weight loss treatment response regardless of binge-eating disorder status and pretreatment weight change.The International journal of eating disorders · 2018Article
- Initial Weight Loss Response as an Indicator for Providing Early Rescue Efforts to Improve Long-term Treatment Outcomes.Current diabetes reports · 2017Review
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveSome adults with comorbid depression and obesity respond well to lifestyle interventions while others have poor outcomes. The objective of this study was to evaluate whether early-treatment weight loss progress predicts clinically significant 6-month weight loss among women with obesity and depression.
methodsWe conducted a secondary analysis of data from 75 women with obesity and depression who received a standard lifestyle intervention. Relative risks (RRs) and 95% confidence intervals (CIs) for achieving ≥5% weight loss by 6 months were calculated based on whether they achieved ≥1 lb/week weight loss in weeks 2-8. Among those on target at week 3, we examined potential subsequent time points at which weight loss progress might identify additional individuals at risk for treatment failure.
resultsAt week 2, women who averaged ≥1 lb/week loss were twice as likely to achieve 5% weight loss by 6 months than those who did not (RR=2.40; 95% CI: 2.32-4.29); weight loss at weeks 3-8 was similarly predictive (RRs=2.02-3.20). Examining weight loss progress at week 3 and subsequently at a time point during weeks 4-8, 52-67% of participants were not on target with their weight loss, and those on target were 2-3 times as likely to achieve 5% weight loss by 6 months (RRs=1.82-2.92).
conclusionWeight loss progress as early as week 2 of treatment predicts weight loss outcomes for women with comorbid obesity and depression, which supports the feasibility of developing stepped care interventions that adjust treatment intensity based on early progress in this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.