Evidence map›Paper›PMID 24745005›Full record

ReviewInternational journal of genomics2014

MicroRNAs in the Neural Retina.

Kalina Andreeva, Nigel G F Cooper

Open access · goldAbstract readReview
In one paragraph

Review in International journal of genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Serum miRNA modulations indicate changes in retinal morphology.Frontiers in molecular neuroscience · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The Role of MicroRNAs in Mitochondria-Mediated Eye Diseases.Frontiers in cell and developmental biology · 2021
    Review
  15. Role of microRNA-25 in high glucose cultured Müller glia.International journal of ophthalmology · 2021
    Article
  16. Article
  17. Article
  18. Targeting Neurovascular Interaction in Retinal Disorders.International journal of molecular sciences · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kalina AndreevaDepartment of Anatomical Sciences and Neurobiology, School of Medicine, University of Louisville, 500 S. Preston Street, Louisville, KY 40292, USA.ORCID 0000-0002-5206-532X
Nigel G F CooperDepartment of Anatomical Sciences and Neurobiology, School of Medicine, University of Louisville, 500 S. Preston Street, Louisville, KY 40292, USA.
University of Louisville · US

Funding

WKU Lead Faculty AwardP20GM103436 · NIGMS · UNIVERSITY OF LOUISVILLE · PI ERIC C ROUCHKA · 2012 to 2026
$60.1M
ZEBRAFISH VISUAL FUNCTION RECOVERY FOLLOWING OPTIC NERVE DAMAGEP20RR016481 · NCRR · UNIVERSITY OF LOUISVILLE · PI COOPER, NIGEL G.F. · 2001 to 2011
$34.8M
The Role of CaMKII in Cell Death and Survival Responses of Retinal Ganglion CellsR01EY017594 · NEI · UNIVERSITY OF LOUISVILLE · PI COOPER, NIGEL G.F. · 2008 to 2011
$1.4M
NCRR NIH HHS P20 RR016481NEI NIH HHS R01 EY017594NIGMS NIH HHS P20 GM103436
6 · The paper itself

Abstract

The health and function of the visual system rely on a collaborative interaction between diverse classes of molecular regulators. One of these classes consists of transcription factors, which are known to bind to DNA and control the transcription activities of their target genes. For a long time, it was thought that the transcription factors were the only regulators of gene expression. More recently, however, a novel class of regulators emerged. This class consists of a large number of small noncoding endogenous RNAs, namely, miRNAs. The miRNAs compose an essential component of posttranscriptional gene regulation, since they ultimately control the fate of gene transcripts. The retina, as a part of the central nervous system, is a well-established model for unraveling the molecular mechanisms underlying neuronal and glial functions. Numerous recent efforts have been made towards identification of miRNAs and their inferred roles in the visual pathway. In this review, we summarize the current state of our knowledge regarding the expression and function of miRNA in the neural retina and we discuss their potential uses as biomarkers for some retinal disorders.

Identifiers

PMID24745005
PMCPMC3972879
OpenAlexW2086443800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.