ArticleWorm2013
Functional analysis of the miRNA-mRNA interaction network in C. elegans.
Article in Worm, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Dynamic mRNA and miRNA expression analysis in response to intermuscular bone development of blunt snout bream (Megalobrama amblycephala).Scientific reports · 2016Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
MicroRNAs (miRNAs) are conserved small non-coding RNAs that typically regulate gene expression by binding to the 3' untranslated region (UTR) of mRNAs. Developmental functions of miRNAs have been extensively studied, but additional roles in various cellular processes remain to be understood. The investigation of the biological importance of individual miRNA-target interactions and the miRNA-target interaction network as a whole has been an exciting and challenging field of study. Here we briefly discuss the contributions our lab has made to our understanding of the physiological impact of this miRNA-network in C. elegans, in the context of recent studies in this advancing field. These studies have advanced our knowledge of the role of miRNAs in ensuring a robust cellular response to different physiological conditions. We briefly outline the genetic, biochemical, and computational strategies utilized to understand miRNA functions and discuss our recent study of the miRNA-interaction network in neurons and potential directions for future studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.