ArticleCase reports in oncological medicine2014
An innocent appearing subcutaneous nodule diagnoses a small cell lung cancer in a never-smoker female.
Article in Case reports in oncological medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 12 citations in OpenAlex.
- Lung squamous cell carcinoma presenting as rare clustered cystic lesions: A case report and review of literature.World journal of clinical cases · 2022Article
- Lung Adenocarcinoma Presenting as a Soft Tissue Metastasis to the Shoulder: A Case Report.Medicina (Kaunas, Lithuania) · 2021Article
- Metastatic Adenocarcinoma of the Lung Presenting as a Soft Tissue Mass.Case reports in surgery · 2021Article
- Primary skin manifestation of non-small-cell lung cancer - a case study.Postepy dermatologii i alergologii · 2019Article
- EML4-ALK-positive lung adenocarcinoma presenting an unusual metastatic pattern in a 29-year-old woman who is alive and well in her third year follow up:A case report.Respiratory medicine case reports · 2017Article
- Clinical features and prognostic factors of small cell lung cancer: A retrospective study in 148 patients.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2016Article
- ADVANCED BRONCHOGENIC CARCINOMA PRESENTING WITH SKIN NODULES - A CASE REPORT.Journal of the West African College of SurgeonsArticle
- Lung cancer presenting as a soft-tissue metastasis.Case reports in oncologyArticle
- ADVANCED BRONCHOGENIC CARCINOMA PRESENTING WITH SKIN NODULES - A CASE REPORT.Journal of the West African College of SurgeonsArticle
- Unusual presentation of lung cancer as skeletal muscle and subcutaneous metastases.Lung India : official organ of Indian Chest SocietyArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lung cancer among never-smokers is recognized as the 7th most common cause of cancer death globally. Adenocarcinoma is the most commonly reported histology. Small cell lung cancer (SCLC) has the strongest association with smoking and is rarely reported in never-smokers. Although lung cancer in never-smokers is more common in women, the overall incidence of SCLC in female never-smokers still remains low. Soft tissue metastases from any cancer are rare with an overall prevalence of 1.8%. Soft tissue metastases from lung primary are uncommon, mostly from adenocarcinoma, and portend a poor prognosis. Cutaneous metastases from SCLC are exceptionally rare with reported incidence of 0.3% to 0.8%. We believe ours is the first reported case of SCLC presenting as subcutaneous nodule, in a never-smoker, otherwise asymptomatic female. The diagnosis of SCLC was made incidentally by the excisional biopsy of the subcutaneous nodule. Subsequent CT chest and PET scan revealed a hypermetabolic right lower lobe spiculated lung mass with adrenal and liver involvement. Platinum and etoposide chemotherapy with prophylactic cranial irradiation was initiated for advanced SCLC, and she required further irinotecan and taxol for subsequent pancreatic and adrenal metastases. With continued deterioration, she died approximately 36 months from diagnosis, while under hospice care.
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