ReviewInternational journal of endocrinology2014
Erectile dysfunction in the elderly: an old widespread issue with novel treatment perspectives.
Review in International journal of endocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.
- Ginseng for erectile dysfunction.The Cochrane database of systematic reviews · 2021Pooled it
- Evaluation of drug interactions of saxagliptin with sildenafil in healthy volunteers.European journal of clinical pharmacology · 2022Trial
- Sleep restriction and testosterone concentrations in young healthy males: randomized controlled studies of acute and chronic short sleep.Sleep health · 2019Trial
- Prevalence of erectile dysfunction and associated factors among newly diagnosed ART naïve men living with HIV: a cross sectional study in Mwanza, Northwestern Tanzania.Frontiers in urology · 2025Article
- Development and validation of a prediction model for ED using machine learning: according to NHANES 2001-2004.Scientific reports · 2024Article
- Anogenital Warts in Geriatrics: Immunosenescence and New Sexual Contacts? A Case Report.Clinical, cosmetic and investigational dermatology · 2024Article
- Large conductance voltage-and calcium-activated KFrontiers in pharmacology · 2024Review
- Inflammatory biomarkers may predict response to phosphodiesterase type 5 inhibitor treatment in patients with erectile dysfunction.Investigative and clinical urology · 2023Article
- The high burden of erectile dysfunction among men living with HIV in northern Tanzania: a call for evidence-based interventions.Frontiers in urology · 2023Article
- Evaluation of Serum Testosterone Levels Following Three Months of SA3X (Spilanthes acmella) Supplementation.Cureus · 2022Article
- Sexual dysfunction damages: A legal database review.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022Article
- Erectile dysfunction among testicular cancer survivors: A systematic review and meta-analysis.Heliyon · 2021Article
- The past, present and future: bespoke surgery for older patients with prostate cancer.Nature reviews. Urology · 2021Article
- A Systematic Review on Rho-Kinase as a Potential Therapeutic Target for the Treatment of Erectile Dysfunction.Research and reports in urology · 2020Review
- Investigating the sexual quality of life and its relationship with general health in older men in Iran.Journal of education and health promotion · 2020Article
- When sex meets age: Family physicians' perspectives about sexual dysfunction among older men and women: A qualitative study from Israel.The European journal of general practice · 2019Article
- Sildenafil citrate use in Addis Ababa: characteristics of users and pharmacists' dispensing practices.International journal of clinical pharmacy · 2018Article
- MAT, a Novel Polyherbal Aphrodisiac Formulation, Enhances Sexual Function and Nrf2/HO-1 Pathway While Reducing Oxidative Damage in Male Rats.Evidence-based complementary and alternative medicine : eCAM · 2018Article
- Effects of Two Different Dosages of Sildenafil on Patients With Erectile Dysfunction.American journal of men's health · 2017Article
- Evaluation of the Causes of Erectile Dysfunction in Patients Undergoing Penile Doppler Ultrasonography in Pakistan.The world journal of men's health · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Erectile dysfunction (ED) is one of the most common chronic diseases affecting men and its prevalence increases with aging. It is also the most frequently diagnosed sexual dysfunction in the older male population. A number of different diseases potentially worsening sexual function may occur in elderly people, together with polypharmacy. Related causes of ED are variable and can include arterial, neurogenic, hormonal, cavernosal, iatrogenic, and psychogenic causes. The aim of the present review was to examine the main aspects of erectile dysfunction going through epidemiology and pathophysiology and revise most of ED in elderly disabled men and in those affected with psychiatric disorders. Lastly we tried to focus on the main aspects of nonpharmacological and pharmacological treatments of ED and the recreational use in the elderly. Phosphodiesterase-5 inhibitors (PDE5-I) are commonly used for on-demand or chronic treatment of ED. It is widely known that PDE5-I have lower response rates in older men than in younger patients, but they have the advantages of ease of use and excellent safety profile, also in the elderly. The old and new PDE5-I as well as the alternative treatments for ED are extensively discussed.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.