Evidence map›Paper›PMID 24744780›Full record

ReviewInternational journal of endocrinology2014

Quality of Life and Sexual Health in the Aging of PCa Survivors.

Mauro Gacci, Elisabetta Baldi, Lara Tamburrino, Beatrice Detti, Lorenzo Livi, Cosimo De Nunzio, Andrea Tubaro, Stavros Gravas, Marco Carini, Sergio Serni

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in International journal of endocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Racial disparities in prostate cancer: a molecular perspective.Frontiers in bioscience (Landmark edition) · 2017
    Review
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Mauro GacciDepartment of Urology, University of Florence, Careggi Hospital, Viale Gramsci 7, 50121 Florence, Italy.
Elisabetta BaldiDepartment of Experimental and Clinical Biomedical Sciences, Section of Clinical Pathophysiology, University of Florence, Italy.ORCID 0000-0003-1154-3433
Lara TamburrinoDepartment of Experimental and Clinical Biomedical Sciences, Section of Clinical Pathophysiology, University of Florence, Italy.
Beatrice DettiRadiotherapy, University Hospital Careggi, University of Florence, Italy.
Lorenzo LiviRadiotherapy, University Hospital Careggi, University of Florence, Italy.
Cosimo De NunzioDepartment of Urology, Sant'Andrea Hospital, University "La Sapienza", Rome, Italy.
Andrea TubaroDepartment of Urology, Sant'Andrea Hospital, University "La Sapienza", Rome, Italy.
Stavros GravasDepartment of Urology, University Hospital of Larissa, Larissa, Greece.
Marco CariniDepartment of Urology, University of Florence, Careggi Hospital, Viale Gramsci 7, 50121 Florence, Italy.
Sergio SerniDepartment of Urology, University of Florence, Careggi Hospital, Viale Gramsci 7, 50121 Florence, Italy.
University of Florence · ITAzienda Ospedaliera Sant'Andrea · ITUniversity Hospital of Larissa · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) is the most common malignancy in elderly men. The progressive ageing of the world male population will further increase the need for tailored assessment and treatment of PCa patients. The determinant role of androgens and sexual hormones for PCa growth and progression has been established. However, several trials on androgens and PCa are recently focused on urinary continence, quality of life, and sexual function, suggesting a new point of view on the whole endocrinological aspect of PCa. During aging, metabolic syndrome, including diabetes, hypertension, dyslipidemia, and central obesity, can be associated with a chronic, low-grade inflammation of the prostate and with changes in the sex steroid pathways. These factors may affect both the carcinogenesis processes and treatment outcomes of PCa. Any treatment for PCa can have a long-lasting negative impact on quality of life and sexual health, which should be assessed by validated self-reported questionnaires. In particular, sexual health, urinary continence, and bowel function can be worsened after prostatectomy, radiotherapy, or hormone treatment, mostly in the elderly population. In the present review we summarized the current knowledge on the role of hormones, metabolic features, and primary treatments for PCa on the quality of life and sexual health of elderly Pca survivors.

Identifiers

PMID24744780
PMCPMC3976934
OpenAlexW1972966088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.