ArticleGastroenterology research and practice2014
Functional outcomes and quality of life after restorative proctocolectomy in paediatric patients: a case-control study.
Article in Gastroenterology research and practice, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 41 citations in OpenAlex.
- Secure Ileal Pouch-Anal Anastomosis for Histologic Indeterminate Colitis.Journal of clinical medicine · 2025Article
- Quality of life after colectomy and ileo-jpouch-anal anastomosis in paediatric patients with ulcerative colitis.Pediatric surgery international · 2024Article
- Salvage surgery for pouch-related complication after ileal pouch-anal anastomosis: a report of two cases.Surgical case reports · 2024Article
- Postoperative complications of colectomy and J-pouch with ileostomy versus without ileostomy in children with inflammatory bowel diseases: a systematic review and meta-analysis.World journal of pediatric surgery · 2022Review
- Inflammatory bowel disease position statement of the Italian Society of Colorectal Surgery (SICCR): ulcerative colitis.Techniques in coloproctology · 2020Review
- Hormonal contraceptives and venous thromboembolism: Are inflammatory bowel disease patients at increased risk? A retrospective study on a prospective database.Annals of medicine and surgery (2012) · 2015Article
- A think tank of the Italian Society of Colorectal Surgery (SICCR) on the surgical treatment of inflammatory bowel disease using the Delphi method: ulcerative colitis.Techniques in coloproctology · 2015Article
- Prophylactic negative pressure wound therapy in colorectal surgery. Effects on surgical site events: current status and call to action.Updates in surgery · 2015Review
- Gastrointestinal endoscopy biopsy derived proteomic patterns predict indeterminate colitis into ulcerative colitis and Crohn's colitis.World journal of gastrointestinal endoscopy · 2015Article
- Pouch-related fistula and intraoperative tricks to prevent it.Techniques in coloproctology · 2015Article
- Gallstone ileus without bilioenteric fistula years after bypass surgery for Crohn's disease. Case report and clues to etiology of a neglected cause of obstruction.International journal of surgery case reports · 2015Article
- Effects of age at disease onset and at treatment on serology in inflammatory bowel diseases.Digestive diseases and sciences · 2015Article
- Surgical site events in colorectal surgery: prevention is better than cure.Techniques in coloproctology · 2014Article
- Ileal pouch fistulas after restorative proctocolectomy: management and outcomes.Techniques in coloproctology · 2014Article
- Surgical treatment of perianal fistulizing Crohn's disease: from lay-open to cell-based therapy--an overview.TheScientificWorldJournal · 2014Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. Restorative proctocolectomy with ileal-pouch anal anastomosis (IPAA) has some peculiarities in paediatric ulcerative colitis (UC). Aims. The primary aim was to compare the bowel function of patients undergoing IPAA between those operated on in childhood and adulthood. The secondary aim was to compare the quality of life (QoL) and outcomes for children between medical and surgical therapies. Method. Children undergoing IPAA were compared with adult patients undergoing IPAA between 2007 and 2012. Function was assessed 1 year after ileostomy closure. Function and QoL of medically managed paediatric patients were compared with their surgical counterparts. Results. Twelve paediatric IPAA patients were compared with 24 adult ones. Acute presentation was common in the former, usually after failed biological treatment. Recurrent pouchitis was more frequent in children. Younger patients exhibited a trend toward better discrimination and continence. QoL was excellent in both groups. Twelve medically treated children were enrolled for secondary aim. Functioning was similar in IPAA- and medically managed children, but the former had a better QoL, confirmed by parents' perception. Conclusions. Similar function is achieved by IPAA in childhood or adulthood. IPAA may offer a better QoL compared to prolonged medical management. The beneficial effects of IPAA experienced by children were similarly observed by their parents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.