ArticleFrontiers in systems neuroscience2014
Time of day influences memory formation and dCREB2 proteins in Drosophila.
Article in Frontiers in systems neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Predicting Performance in Working Memory During the Waking Period by Applying a Convolutional Neural Network to EEG Data in the N-Back Task: A Pilot Study.Sensors (Basel, Switzerland) · 2026Article
- The circadian genes are required in DAL neurons forFrontiers in neuroscience · 2025Article
- Circadian Rhythms in Fear Extinction Recall Depend on the Time of Day of Extinction Recall, Not the Time of Day of Extinction Learning.Journal of biological rhythms · 2023Article
- Circadian disruption of memory consolidation inFrontiers in systems neuroscience · 2023Article
- CREBB repression of protein synthesis in mushroom body gates long-term memory formation inProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Central and Peripheral Clock Control of Circadian Feeding Rhythms.Journal of biological rhythms · 2021Article
- Neurofibromin 1 in mushroom body neurons mediates circadian wake drive through activating cAMP-PKA signaling.Nature communications · 2021Article
- CREBA and CREBB in two identified neurons gate long-term memory formation inProceedings of the National Academy of Sciences of the United States of America · 2021Article
- Sleep drive reconfigures wake-promoting clock circuitry to regulate adaptive behavior.PLoS biology · 2021Article
- Regulation of Olfactory Associative Memory by the Circadian Clock Output Signal Pigment-Dispersing Factor (PDF).The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- The clock gene period differentially regulates sleep and memory in Drosophila.Neurobiology of learning and memory · 2018Article
- Neuroanatomical details of the lateral neurons of Drosophila melanogaster support their functional role in the circadian system.The Journal of comparative neurology · 2018Article
- A kinase-dependent feedforward loop affects CREBB stability and long term memory formation.eLife · 2018Article
- Circadian Modulation of Alcohol-Induced Sedation and Recovery in Male and Female Drosophila.Journal of biological rhythms · 2016Article
- Misaligned feeding impairs memories.eLife · 2015Article
- Synchrony and desynchrony in circadian clocks: impacts on learning and memory.Learning & memory (Cold Spring Harbor, N.Y.) · 2015Review
- Spatio-temporal in vivo recording of dCREB2 dynamics in Drosophila long-term memory processing.Neurobiology of learning and memory · 2015Article
- Waking up to the alarm: sleep, clocks, and making memory (s)tick.Frontiers in systems neuroscience · 2015Article
- Circadian Clock Dysfunction and Psychiatric Disease: Could Fruit Flies have a Say?Frontiers in neurology · 2015Review
- Unraveling the complexities of circadian and sleep interactions with memory formation through invertebrate research.Frontiers in systems neuroscience · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Many biological phenomena oscillate under the control of the circadian system, exhibiting peaks and troughs of activity across the day/night cycle. In most animal models, memory formation also exhibits this property, but the underlying neuronal and molecular mechanisms remain unclear. The dCREB2 transcription factor shows circadian regulated oscillations in its activity, and has been shown to be important for both circadian biology and memory formation. We show that the time-of-day (TOD) of behavioral training affects Drosophila memory formation. dCREB2 exhibits complex changes in protein levels across the daytime and nighttime, and these changes in protein abundance are likely to contribute to oscillations in dCREB2 activity and TOD effects on memory formation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.