Evidence map›Paper›PMID 24744579›Full record

SynthesisWorld journal of gastroenterology2014

Extent of lymphadenectomy and perioperative therapies: two open issues in gastric cancer.

Andrea Giuliani, Michelangelo Miccini, Luigi Basso

Abstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Extent of lymph node dissection for adenocarcinoma of the stomach.The Cochrane database of systematic reviews · 2015
    Pooled it
  2. Review
  3. Review
  4. Adenocarcinoma Arising in a Gastric Duplication Cyst.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Validation of the American Joint Committee on Cancer (AJCC) 8th edition stage system for gastric cancer patients: a population-based analysis.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2018
    Article
  9. Review
  10. Article
  11. Gastric cancer: Current status of lymph node dissection.World journal of gastroenterology · 2016
    Review
  12. Review on the Applications and Molecular Mechanisms of Xihuang Pill in Tumor Treatment.Evidence-based complementary and alternative medicine : eCAM · 2015
    Review
  13. Surgical interventions for gastric cancer: a review of systematic reviews.International journal of clinical and experimental medicine · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andrea GiulianiAndrea Giuliani, Michelangelo Miccini, Luigi Basso, Department of Surgery "Pietro Valdoni", "Sapienza" University of Rome, Medical School, Policlinico "Umberto I", 00161 Rome, Italy.
Michelangelo MicciniAndrea Giuliani, Michelangelo Miccini, Luigi Basso, Department of Surgery "Pietro Valdoni", "Sapienza" University of Rome, Medical School, Policlinico "Umberto I", 00161 Rome, Italy.
Luigi BassoAndrea Giuliani, Michelangelo Miccini, Luigi Basso, Department of Surgery "Pietro Valdoni", "Sapienza" University of Rome, Medical School, Policlinico "Umberto I", 00161 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer is one of the leading causes of death for cancer worldwide, although geographical variations in incidence exist. Over the last decades, its incidence and mortality have gradually decreased in Western countries, while these have increased, or remained stable, in the other world regions. Gastric cancer is often diagnosed at an advanced stage, with the only notable exception of Japan, where nationwide screening programs are enforced, due to local high incidence. Curative- intent surgery (i.e., gastrectomy, total or partial, and lymphadenectomy) remains the cornerstone of treatment of gastric cancer. Much has been debated about the extent of lymph node dissection and, although it is a valuable contribution to staging and cure, operative treatment only represents one aspect of overall effective management, as the risk of both locoregional and distant recurrences are high, and bear a poor prognosis. As a matter of fact, surgery, as a single modality treatment, has probably achieved its maximum efficacy for local control and survival, while other accompanying nonsurgical treatment modalities have to be taken into account, although their role is still the subject of considerable debate. The authors in this review present an update on the outcome of treatment of gastric cancer in relation to the extent of lymphadenectomy and of various nonsurgical preoperative, intraoperative, and postoperative strategies.

Indexed as

Lymph Node ExcisionAntineoplastic AgentsChemotherapy, AdjuvantGastrectomyHumansInfusions, ParenteralJapanLymphatic MetastasisNeoadjuvant TherapyNeoplasm Recurrence, LocalPerioperative PeriodPostoperative PeriodPreoperative PeriodRadiotherapyStomachStomach NeoplasmsAntineoplastic AgentsAdenocarcinomaChemoradiotherapyChemotherapyGastric cancerIntraperitonealMeta-analysisPostoperativePreoperativeRadiotherapyRandomized controlled trial

Identifiers

PMID24744579
PMCPMC3983445

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.