ReviewJournal of Indian Society of Periodontology2014
Microbial role in periodontitis: Have we reached the top? Some unsung bacteria other than red complex.
Review in Journal of Indian Society of Periodontology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Microbial colonisation associated with conventional and self-ligating brackets: a systematic review.Journal of orthodontics · 2022Pooled it
- Efficacy of ILIB on periodontal clinical parameters and glycemic control in patients with periodontitis and type II diabetes-randomized clinical trial.Lasers in medical science · 2022Trial
- Clinical Profile, Risk Factors, and Microbial Dysbiosis in Periodontitis: Findings from an Adult Cohort and Microbiome-Based Predictive Models.Journal of clinical medicine · 2026Article
- Exploring the Link Between Periodontitis and Alzheimer's Disease-Could a Nanoparticulate Vaccine Break It?Pharmaceutics · 2025Review
- Microbiological and molecular aspects of periodontitis pathogenesis: an infection-induced inflammatory condition.Frontiers in cellular and infection microbiology · 2025Review
- Feasibility and preliminary findings of a bacterial diversity study in periodontitis: a pilot investigation from the Western Cape.Frontiers in oral health · 2025Article
- Dental calculus as a proxy for animal microbiomes.Quaternary international : the journal of the International Union for Quaternary Research · 2023Article
- Autophagy in aging-related oral diseases.Frontiers in endocrinology · 2022Review
- Pathological and Therapeutic Approach to Endotoxin-Secreting Bacteria Involved in Periodontal Disease.Toxins · 2021Review
- The effect of lipoxin A4 on E. coli LPS-induced osteoclastogenesis.Clinical oral investigations · 2021Article
- Adhesion of anaerobic periodontal pathogens to extracellular matrix proteins.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020Review
- Human oral microbiome dysbiosis as a novel non-invasive biomarker in detection of colorectal cancer.Theranostics · 2020Observational
- Oral microbiome diversity in chimpanzees from Gombe National Park.Scientific reports · 2019Article
- Article
- Comparative pan genome analysis of oral Prevotella species implicated in periodontitis.Functional & integrative genomics · 2017Article
- Subgingival dysbiosis in smoker and non‑smoker patients with chronic periodontitis.Molecular medicine reports · 2017Article
- Detection and comparison of prevalence ofJournal of oral and maxillofacial pathology : JOMFPArticle
- Novel Pathogens in Periodontal Microbiology.Journal of pharmacy & bioallied sciencesReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The microbial etiology of periodontal disease has been the focus of researchers for a long time. The search for the pathogens of periodontal diseases has been underway for more than 100 years, and continues up today. Despite the increasing knowledge about oral microbiota, we are not able to implicate any one particular organism that can be considered as a candidate pathogen. In fact the term "candidate pathogen" has lost its steam with a myriad of microorganisms being incriminated from time to time. Most studies of the bacterial etiology of periodontitis have used either culture-based or targeted deoxyribonucleic acid approaches and so it is likely that pathogens remain undiscovered. The advent of 16S cloning and sequencing has facilitated identification of several uncultivable bacteria in the oral cavity. The concept that not one single organism, but several organisms contained in the biofilm orchestrating in a medley of the show appears to be more plausible. The present review highlights some lesser known bacteria associated with periodontal destruction.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.