ArticleBiology of sport2013
The association of gene polymorphisms with athlete status in ukrainians.
Article in Biology of sport, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 5 of them syntheses that pooled it.
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Who cites it
42 citing papers in PubMed, 5 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Pooled it
- Candidate gene polymorphisms and power athlete status: a meta-analytical approach.Journal of physiology and biochemistry · 2025Pooled it
- Role of theInternational journal of environmental research and public health · 2024Pooled it
- Examining the relationship between genetic polymorphisms (BDKRB2, GNB3, HIF1A, MCT1, NOS3) and endurance athlete status.European journal of applied physiology · 2024Pooled it
- Genes and Elite Marathon Running Performance: A Systematic Review.Journal of sports science & medicine · 2019Pooled it
- Nutrigenetic Markers Related to Nutrient Metabolism, Recovery, and Performance in Athletes: a Review of Current Evidence.Current nutrition reports · 2026Review
- University-based physical education as a structured temporal and spatial opportunity for shaping health-oriented lifestyles.Frontiers in public health · 2025Article
- How Much Can the Genotype Predict Phenotypical Power Performance in Elite Male and Female Athletes?Journal of human kinetics · 2025Article
- Importance of selected genetic determinants on endurance performance and physical strength: a narrative review.Frontiers in physiology · 2025Review
- Testing in Football: A Narrative Review.Sports (Basel, Switzerland) · 2024Review
- The association of back pain with physical inactivity and hypothyroidism in pregnant women.Journal of back and musculoskeletal rehabilitation · 2024Article
- The Role of AGT, AMPD1, HIF1α, IL-6 Gene Polymorphisms in the Athletes' Power Status: A Meta-Analysis.Journal of human kinetics · 2023Article
- Genes and Athletic Performance: The 2023 Update.Genes · 2023Review
- Article
- The Effect of Selected Polymorphisms of theGenes · 2022Article
- Polygenic Models Partially Predict Muscle Size and Strength but Not Low Muscle Mass in Older Women.Genes · 2022Article
- Article
- Genetic characteristics of competitive swimmers: a review.Biology of sport · 2022Review
- Review
- Genetic Profile in Genes Associated with Cardiorespiratory Fitness in Elite Spanish Male Endurance Athletes.Genes · 2021Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledAthletic performance is a polygenic trait influenced by both environmental and genetic factors.
objectiveTo investigate individually and in combination the association of common gene polymorphisms with athlete status in Ukrainians.
methodsA total of 210 elite Ukrainian athletes (100 endurance-oriented and 110 power-orientated athletes) and 326 controls were genotyped for ACE I/D, HIF1A Pro582Ser, NOS3 -786 T/C, PPARA intron 7 G/C, PPARG Pro12Ala and PPARGC1B Ala203Pro gene polymorphisms, most of which were previously reported to be associated with athlete status or related intermediate phenotypes in different populations.
resultsPower-oriented athletes exhibited an increased frequency of the HIF1A Ser (16.1 vs. 9.4%, P = 0.034) and NOS3 T alleles (78.3 vs. 66.2%, P = 0.0019) in comparison with controls. Additionally, we found that the frequency of the PPARG Ala allele was significantly higher in power-oriented athletes compared with the endurance-oriented athletes (24.7 vs. 13.5%; P = 0.0076). Next, we determined the total genotype score (TGS, from the accumulated combination of the three polymorphisms, with a maximum value of 100 for the theoretically optimal polygenic score) in athletes and controls. The mean TGS was significantly higher in power-oriented athletes (39.1 ± 2.3 vs. 32.6 ± 1.5; P = 0.0142) than in controls.
conclusionsWe found that the HIF1A Ser, NOS3 T and PPARG Ala alleles were associated with power athlete status in Ukrainians.
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