ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2014
Clinical characteristics, pathological features and surgical outcomes of focal cortical dysplasia (FCD) type II: correlation with pathological subtypes.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Age at onset of epilepsy shapes neurocognitive profiles in focal cortical dysplasia.Journal of neurology · 2025Article
- Prognostic analysis in children with focal cortical dysplasia II undergoing epilepsy surgery: Clinical and radiological factors.Frontiers in neurology · 2023Article
- Surgical Outcome in Extratemporal Epilepsies Based on Multimodal Pre-Surgical Evaluation and Sequential Intraoperative Electrocorticography.Behavioral sciences (Basel, Switzerland) · 2021Article
- Focal cortical dysplasia: etiology, epileptogenesis, classification, clinical presentation, imaging, and management.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Review
- Polymorphous low-grade neuroepithelial tumor of the young: case report and review focus on the radiological features and genetic alterations.BMC neurology · 2020Review
- Radiologic and Pathologic Features of the Transmantle Sign in Focal Cortical Dysplasia: The T1 Signal Is Useful for Differentiating Subtypes.AJNR. American journal of neuroradiology · 2019Article
- Post-processing of structural MRI for individualized diagnostics.Quantitative imaging in medicine and surgery · 2015Review
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8 authors.
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Abstract
Focal cortical dysplasia (FCD) type II is a major cause of drug-resistant epilepsy. In order to gain insight into the possible correlations between FCD II pathological pattern and different clinical characteristics (including clinical information, imaging characteristics and surgical outcomes), different clinicopathological characteristics in two types of FCD II were analyzed (especially in FCD IIb). The mean age of seizure onset and disease duration of 78 patients was 11.0 and 11.2 years, respectively. Patients with FCD type IIb had earlier seizure onset compared with those with FCD type IIa. Pathological subtype IIb was predominantly in frontal lobe and subtype IIa was predominantly seen in temporal. Type IIb demonstrated significantly more signal abnormalities in fluid attenuated inversion recovery (FLAIR) images and T2 images than Type IIa. The rate of satisfactory seizure outcome was 67.64 % in the FCD IIa group, while relative higher, 88.63 %, in the FCD IIb group. All these characteristics may assist in their earlier diagnosis and improve the predictability of surgical management.
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