Evidence map›Paper›PMID 24743868›Full record

ReviewCurrent atherosclerosis reports2014

Renal artery stenosis-when to screen, what to stent?

Claudine G Jennings, John G Houston, Alison Severn, Samira Bell, Isla S Mackenzie, Thomas M Macdonald

Abstract readReview
In one paragraph

Review in Current atherosclerosis reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. [Austrian Consensus on High Blood Pressure 2019].Wiener klinische Wochenschrift · 2019
    Article
  5. Article
  6. Renal artery stenosis in China: The state of changes.Journal of clinical hypertension (Greenwich, Conn.) · 2018
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Claudine G JenningsMedicines Monitoring Unit and Hypertension Research Centre, Ninewells Hospital and University of Dundee, Dundee, DD1 9SY, UK, claudine@memo.dundee.ac.uk.
John G Houston
Alison Severn
Samira Bell
Isla S Mackenzie
Thomas M Macdonald

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal artery stensosis (RAS) continues to be a problem for clinicians, with no clear consensus on how to investigate and assess the clinical significance of stenotic lesions and manage the findings. RAS caused by fibromuscular dysplasia is probably commoner than previously appreciated, should be actively looked for in younger hypertensive patients and can be managed successfully with angioplasty. Atheromatous RAS is associated with increased incidence of cardiovascular events and increased cardiovascular mortality, and is likely to be seen with increasing frequency. Evidence from large clinical trials has led clinicians away from recommending interventional revascularisation towards aggressive medical management. There is now interest in looking more closely at patient selection for intervention, with focus on intervening only in patients with the highest-risk presentations such as flash pulmonary oedema, rapidly declining renal function and severe resistant hypertension. The potential benefits in terms of improving hard cardiovascular outcomes may outweigh the risks of intervention in this group, and further research is needed.

Indexed as

StentsAngioplastyAntihypertensive AgentsAtherosclerosisHumansHypertensionRenal Artery ObstructionAntihypertensive Agents

Identifiers

PMID24743868
PMCPMC4010717

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.