Trial reportStroke2014
Sleep duration and risk of stroke mortality among Chinese adults: Singapore Chinese health study.
Trial report in Stroke, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03554954 (Association Between Food/Nutrient Intake and Sleep Quality in Middle Aged and Older Population), which is not on this map. Cited by 46 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Association Between Food/Nutrient Intake and Sleep Quality in Middle Aged and Older Population
Who cites it
46 citing papers in PubMed, 8 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- The Association Between Sleep Duration and the Risk of Hypertension: A Systematic Review and Meta-analysis of Cohort Studies.Journal of general internal medicine · 2025Pooled it
- Inadequate sleep increases stroke risk: evidence from a comprehensive meta-analysis of incidence and mortality.GeroScience · 2025Pooled it
- Sleep duration and risk of cardio-cerebrovascular disease: A dose-response meta-analysis of cohort studies comprising 3.8 million participants.Frontiers in cardiovascular medicine · 2022Pooled it
- Sleep Duration/Quality With Health Outcomes: An Umbrella Review of Meta-Analyses of Prospective Studies.Frontiers in medicine · 2021Pooled it
- Adherence to the Mediterranean diet and risk of stroke and stroke subtypes.European journal of epidemiology · 2019Pooled it
- Self-Reported Sleep Duration and Quality and Cardiovascular Disease and Mortality: A Dose-Response Meta-Analysis.Journal of the American Heart Association · 2018Pooled it
- Relationship of Sleep Duration With All-Cause Mortality and Cardiovascular Events: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.Journal of the American Heart Association · 2017Pooled it
- Sleep duration and risk of fatal and nonfatal stroke: a prospective study and meta-analysis.Neurology · 2015Pooled it
- Can sleep quality and wellbeing be improved by changing the indoor lighting in the homes of healthy, elderly citizens?Chronobiology international · 2015Trial
- Association between sleep duration from midlife and the risk of physical frailty in late life.Scientific reports · 2026Article
- Sleep Disorders and Stroke: Pathophysiological Links, Clinical Implications, and Management Strategies.Medical sciences (Basel, Switzerland) · 2025Review
- Prestroke sleep and stroke: a narrative review.Sleep & breathing = Schlaf & Atmung · 2025Review
- Social disadvantage, insufficient sleep, and cardiovascular disease.Frontiers in sleep · 2025Review
- Review
- Pre-morbid sleep disturbance and its association with stroke severity: results from the international INTERSTROKE study.European journal of neurology · 2024Article
- Exploring the potential relationship between short sleep risks and cognitive function from the perspective of inflammatory biomarkers and cellular pathways: Insights from population-based and mice studies.CNS neuroscience & therapeutics · 2024Article
- Correlation between sleep duration and prevalence of hypertension: the China Health and Nutrition Survey.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2024Article
- Sleep duration and risk of stroke and coronary heart disease: a 9-year community-based prospective study of 0.5 million Chinese adults.BMC neurology · 2023Article
- Long Sleep Duration and Stroke-Highly Linked, Poorly Understood.Neurology international · 2023Review
- Sleep Patterns and the Risk of Acute Stroke: Results From the INTERSTROKE International Case-Control Study.Neurology · 2023Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
background and purposeProspective relation between sleep duration and stroke risk is less studied, particularly in Asians. We examined the association between sleep duration and stroke mortality among Chinese adults.
methodsThe Singapore Chinese Health Study is a population-based cohort of 63 257 Chinese adults aged 45 to 74 years enrolled during 1993 through 1998. Sleep duration at baseline was assessed via in-person interview, and death information during follow-up was ascertained via record linkage with the death registry up to December 31, 2011. Cox proportional hazard models were used to calculate hazard ratios with adjustment for other comorbidities and lifestyle risk factors of stroke mortality.
resultsDuring 926 752 person-years of follow-up, we documented 1381 stroke deaths (322 from hemorrhagic and 1059 from ischemic or nonspecified strokes). Compared with individuals with 7 hours per day of sleep, the multivariate-adjusted hazard ratio (95% confidence interval) of total stroke mortality was 1.25 (1.05-1.50) for ≤5 hours per day (short duration), 1.01 (0.87-1.18) for 6 hours per day, 1.09 (0.95-1.26) for 8 hours per day, and 1.54 (1.28-1.85) for ≥9 hours per day (long duration). The increased risk of stroke death with short (1.54; 1.16-2.03) and long durations of sleep (1.95; 1.48-2.57) was seen among subjects with a history of hypertension, but not in those without hypertension. These findings were limited to risk of death from ischemic or nonspecified stroke, but not observed for hemorrhagic stroke.
conclusionsBoth short and long sleep durations are associated with increased risk of stroke mortality in a Chinese population, particularly among those with a history of hypertension.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.