ReviewModern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc2015
Familial colorectal cancer type X: genetic profiles and phenotypic features.
Review in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Resolving the Haplotype Complexity of Colorectal Cancer Genomes with Droplet Barcode Sequencing.Life (Basel, Switzerland) · 2026Article
- Hereditary Colorectal Cancer: Clinical Implications of Genomic Medicine and Precision Oncology.Journal of the anus, rectum and colon · 2025Review
- New insights on familial colorectal cancer type X syndrome.Scientific reports · 2022Article
- Comparison Between Familial Colorectal Cancer Type X and Lynch Syndrome: Molecular, Clinical, and Pathological Characteristics and Pedigrees.Frontiers in oncology · 2020Article
- Colorectal Cancer in the Adolescent and Young Adult Population.JCO oncology practice · 2020Article
- Current clinical topics of Lynch syndrome.International journal of clinical oncology · 2019Review
- Risks of Colorectal Cancer and Cancer-Related Mortality in Familial Colorectal Cancer Type X and Lynch Syndrome Families.Journal of the National Cancer Institute · 2019Article
- Prevalence and spectrum ofHereditary cancer in clinical practice · 2019Article
- Identification of genetic variants for clinical management of familial colorectal tumors.BMC medical genetics · 2018Article
- Familial Associations of Colorectal Cancer with Other Cancers.Scientific reports · 2017Article
- Familial Colorectal Cancer Type X in Central Iran: A New Clinicopathologic Description.International journal of hematology-oncology and stem cell research · 2017Article
- Germline INDELs and CNVs in a cohort of colorectal cancer patients: their characteristics, associations with relapse-free survival time, and potential time-varying effects on the risk of relapse.Cancer medicine · 2017Article
- Differential expression of CK20, β-catenin, and MUC2/5AC/6 in Lynch syndrome and familial colorectal cancer type X.BMC clinical pathology · 2017Article
- DNA Methylation Identifies Loci Distinguishing Hereditary Nonpolyposis Colorectal Cancer Without Germ-Line MLH1/MSH2 Mutation from Sporadic Colorectal Cancer.Clinical and translational gastroenterology · 2016Article
- Update on Lynch syndrome genomics.Familial cancer · 2016Review
- Germline variants in the SEMA4A gene predispose to familial colorectal cancer type X.Nature communications · 2014Article
- Immunoprofiles of colorectal cancer from Lynch syndrome.OncoimmunologyArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heredity is a major cause of colorectal cancer, but although several rare high-risk syndromes have been linked to disease-predisposing mutations, the genetic mechanisms are undetermined in the majority of families suspected of hereditary cancer. We review the clinical presentation, histopathologic features, and the genetic and epigenetic profiles of the familial colorectal cancer type X (FCCTX) syndrome with the aim to delineate tumor characteristics that may contribute to refined diagnostics and optimized tumor prevention.
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Registered trials
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