ReviewJournal of electrocardiology
Acute myocardial ischemia: cellular mechanisms underlying ST segment elevation.
Review in Journal of electrocardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Electrophysiological Mechanisms of ST Segment and T-Wave Changes: Insights into Ischemia, Conduction Delay, Hypertrophy, and Electrolyte Disturbance.Annals of cardiac anaesthesia · 2026Review
- Article
- A refined, minimally invasive, reproducible ovine ischaemia-reperfusion-infarction model using implantable defibrillators: Methodology and validation.Experimental physiology · 2025Article
- Myocardial ischemia simulation based on a multi-scale heart electrophysiology model.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024Article
- Regional beat-to-beat variability of repolarization increases during ischemia and predicts imminent arrhythmias in a pig model of myocardial infarction.American journal of physiology. Heart and circulatory physiology · 2023Article
- Non-ST-segment elevation myocardial infarction with non-obstructive coronary arteries due to a type-A thymoma: A case report.Heliyon · 2023Article
- Article
- The Spiked Helmet Sign Predicting a Poor Outcome in a Patient with Non-Myocardial Infarction ST-Segment Elevation.Medicina (Kaunas, Lithuania) · 2021Article
- [Detection of ECG alterations typical for myocardial ischemia : New methods 2021].Der Internist · 2021Review
- Cognition and progress of de Winter electrocardiogram pattern.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021Article
- Myocardial Infarction with and without ST-segment Elevation: a Contemporary Reappraisal of Similarities and Differences.Current cardiology reviews · 2021Review
- Variant Angina with Spontaneously Documented Ischemia- and Tachycardia-induced "Lambda" Waves.Internal medicine (Tokyo, Japan) · 2021Article
- A proximal right coronary artery occlusion presenting with ST-segment depression in leads II, III, and aVF.Anatolian journal of cardiology · 2020Article
- Ionic mechanisms of ST segment elevation in electrocardiogram during acute myocardial infarction.The journal of physiological sciences : JPS · 2020Article
- Transient appearance of Brugada-like Type 1 electrocardiogram pattern immediately after biphasic synchronized electrical cardioversion for atrial fibrillation: a case series.European heart journal. Case reports · 2019Article
- Significance of New, Isolated T-wave Inversion in Multiple Electrocardiogram Leads with Regadenoson Injection in Patients with Normal Myocardial Perfusion Imaging: An Observational Report of 5 Consecutive Cases.Kansas journal of medicine · 2019Article
- Pretreatment with neuregulin-1 improves cardiac electrophysiological properties in a rat model of myocardial infarction.Experimental and therapeutic medicine · 2019Article
- "Lambda-wave" ST-elevation is associated with severe prognosis in stress (takotsubo) cardiomyopathy.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2018Article
- Observational
- The de winter electrocardiogram pattern is a transient electrocardiographic phenomenon that presents at the early stage of ST-segment elevation myocardial infarction.Clinical cardiology · 2018Article
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Authors and funding
2 authors.
Funding
Abstract
The electrocardiogram (ECG) is an essential tool for the diagnosis of acute myocardial ischemia in the emergency department, as well as for that of an evolving acute myocardial infarction (AMI). Changes in the surface ECG in leads whose positive poles face the ischemic region are known to be related to injury currents flowing across the boundaries between the ischemic and the surrounding normal myocardium. Although experimental studies have also shown an endocardium to epicardium differential sensitivity to the effect of acute ischemia, the important contribution of this transmural heterogeneous response to the changes observed in the surface ECG is less appreciated by the clinical cardiologist. This review briefly discusses our current knowledge regarding the electrophysiology of the ischemic myocardium focusing primarily on the electrophysiologic changes underlying the ECG alterations observed at the onset of a transmural AMI.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.