Evidence map›Paper›PMID 24742470›Full record

ReviewThe Journal of nutritional biochemistry2014

Dietary antiaging phytochemicals and mechanisms associated with prolonged survival.

Hongwei Si, Dongmin Liu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Journal of nutritional biochemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
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  10. Article
  11. Anticancer Properties of Garlic and Ginger Extract in Colon Cancer Cell Line.Asian Pacific journal of cancer prevention : APJCP · 2024
    Article
  12. Review
  13. Review
  14. A Diet Supplemented with Oil-Free Olive Pulp Flour (MOP-ManniOlivePowderAnimals : an open access journal from MDPI · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hongwei SiDepartment of Family and Consumer Sciences, Tennessee State University, Nashville, TN 37209, USA. Electronic address: hsi@tnstate.edu.
Dongmin LiuDepartment of Human Nutrition, Foods and Exercise, College of Agriculture and Life Sciences, Virginia Tech, Blacksburg, VA 24061, USA. Electronic address: doliu@vt.edu.

Funding

Identification and molecular characterization of anti-diabetic flavonoidsR01AT007077 · NCCIH · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI LIU, DONGMIN · 2012 to 2016
$1.9M
NCCIH NIH HHS 1R01AT007077-01NCCIH NIH HHS R01 AT007077
6 · The paper itself

Abstract

Aging is well-known an inevitable process that is influenced by genetic, lifestyle and environmental factors. However, the exact mechanisms underlying the aging process are not well understood. Increasing evidence shows that aging is highly associated with chronic increase in reactive oxygen species (ROS), accumulation of a low-grade proinflammatory phenotype and reduction in age-related autophagy, suggesting that these factors may play important roles in promoting aging. Indeed, reduction of ROS and low-grade inflammation and promotion of autophagy by calorie restriction or other dietary manipulation can extend lifespan in a wide spectrum of model organisms. Interestingly, recent studies show that some food-derived small molecules, also called phytochemicals, can extend lifespan in various animal species. In this paper, we review several recently identified potential antiaging phytochemicals that have been studied in cells, animals and humans and further highlight the cellular and molecular mechanisms underlying the antiaging actions by these molecules.

Indexed as

DietDietary SupplementsEvidence-Based MedicineHealth PromotionLongevityNutrition PolicyAnimalsAnti-Inflammatory Agents, Non-SteroidalAntioxidantsAutophagyCaloric RestrictionHumansPhytochemicalsAnti-Inflammatory Agents, Non-SteroidalAntioxidantsPhytochemicalsAgingAutophagyCalorie restrictionInflammationPhytochemicalsReactive oxygen species

Identifiers

PMID24742470
PMCPMC4019696

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.