Evidence map›Paper›PMID 24742268›Full record

ArticleBMC cancer2014

Feasibility of intensity-modulated and image-guided radiotherapy for locally advanced esophageal cancer.

Nam P Nguyen, Siyoung Jang, Jacqueline Vock, Vincent Vinh-Hung, Alexander Chi, Paul Vos, Judith Pugh, Richard A Vo, Misty Ceizyk, Anand Desai and 2 more

Abstract read
In one paragraph

Article in BMC cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nam P NguyenDepartment of Radiation Oncology, Howard University Hospital, 2401 Georgia Avenue, N,W,, Room 2055, Washington, DC 20060, USA. NamPhong.Nguyen@yahoo.com.
Siyoung Jang
Jacqueline Vock
Vincent Vinh-Hung
Alexander Chi
Paul Vos
Judith Pugh
Richard A Vo
Misty Ceizyk
Anand Desai
Lexie Smith-Raymond
International Geriatric Radiotherapy Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this study the feasibility of intensity-modulated radiotherapy (IMRT) and tomotherapy-based image-guided radiotherapy (IGRT) for locally advanced esophageal cancer was assessed.

methodsA retrospective study of ten patients with locally advanced esophageal cancer who underwent concurrent chemotherapy with IMRT (1) and IGRT (9) was conducted. The gross tumor volume was treated to a median dose of 70 Gy (62.4-75 Gy).

resultsAt a median follow-up of 14 months (1-39 months), three patients developed local failures, six patients developed distant metastases, and complications occurred in two patients (1 tracheoesophageal fistula, 1 esophageal stricture requiring repeated dilatations). No patients developed grade 3-4 pneumonitis or cardiac complications.

conclusionsIMRT and IGRT may be effective for the treatment of locally advanced esophageal cancer with acceptable complications.

Indexed as

AgedEsophageal NeoplasmsFemaleHumansMaleMiddle AgedNeoplasm Recurrence, LocalRadiotherapy DosageRadiotherapy, Image-GuidedRadiotherapy, Intensity-Modulated

Identifiers

PMID24742268
PMCPMC3996254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.