Trial reportJournal of alternative and complementary medicine (New York, N.Y.)2014
Effects of olfactory stimulation from the fragrance of the Japanese citrus fruit yuzu (Citrus junos Sieb. ex Tanaka) on mood states and salivary chromogranin A as an endocrinologic stress marker.
Trial report in Journal of alternative and complementary medicine (New York, N.Y.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 58 citations in OpenAlex.
- Effects of heat-treatedFrontiers in nutrition · 2026Trial
- Increase in diastolic blood pressure induced by fragrance inhalation of grapefruit essential oil is positively correlated with muscle sympathetic nerve activity.The journal of physiological sciences : JPS · 2020Trial
- A Randomized Controlled Trial for the Effectiveness of Aromatherapy in Decreasing Salivary Gland Damage following Radioactive Iodine Therapy for Differentiated Thyroid Cancer.BioMed research international · 2016Trial
- Efficacy of Fragrance Types and Intervention Methods in Reducing Driver Fatigue and Modulating Emotional Development Assessed by HRV and Subjective Indicators.Sensors (Basel, Switzerland) · 2025Article
- Multisensory nature-based Recharge Rooms' effect on healthcare workers in a multicenter study.Frontiers in psychology · 2025Article
- Antistress Effects of Terpinen-4-ol and Compounds of Mimicked Yuzu Synthetic Fragrance in Humans and Mice.Foods (Basel, Switzerland) · 2024Article
- Alleviation of acute stress response by black pepper aroma administration.Journal of physiological anthropology · 2024Article
- Alleviation of physiological stress response by apple aroma.Australian journal of psychology · 2024Article
- The Effects of Essential Oils on the Nervous System: A Scoping Review.Molecules (Basel, Switzerland) · 2023Article
- Therapeutic Effect and Mechanisms of Essential Oils in Mood Disorders: Interaction between the Nervous and Respiratory Systems.International journal of molecular sciences · 2021Review
- Article
- Multisensory, Nature-Inspired Recharge Rooms Yield Short-Term Reductions in Perceived Stress Among Frontline Healthcare Workers.Frontiers in psychology · 2020Article
- Outcomes of Visual Self-Expression in Virtual Reality on Psychosocial Well-Being With the Inclusion of a Fragrance Stimulus: A Pilot Mixed-Methods Study.Frontiers in psychology · 2020Article
- Dietary Polyphenol Intake and Depression: Results from the Mediterranean Healthy Eating, Lifestyle and Aging (MEAL) Study.Molecules (Basel, Switzerland) · 2018Article
- A Review of Selected Studies That Determine the Physical and Chemical Properties of Saliva in the Field of Dental Treatment.BioMed research international · 2018Review
- The Effectiveness of Aromatherapy for Depressive Symptoms: A Systematic Review.Evidence-based complementary and alternative medicine : eCAM · 2017Review
- Aromatic effects of a Japanese citrus fruit-yuzu (Citrus junos Sieb. ex Tanaka)-on psychoemotional states and autonomic nervous system activity during the menstrual cycle: a single-blind randomized controlled crossover study.BioPsychoSocial medicine · 2016Article
- Psychophysiological and cognitive effects of strawberry plants on people in isolated environments.Journal of Zhejiang University. Science. BArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study investigated the soothing effects of fragrance from yuzu, a Japanese citrus fruit (Citrus junos Sieb. ex Tanaka), with salivary chromogranin A (CgA) used as an endocrinologic stress marker reflecting sympathetic nervous system activity.
methodsTwenty healthy women (mean age, 20.5 ± 0.1 years) participated in a randomized, controlled, crossover study. Participants were examined on two separate occasions-once using the yuzu scent and once using unscented water as a control-in the follicular phase. This experiment measured salivary CgA and the Profile of Mood States (POMS) as a psychological index before and after the aromatic stimulation.
resultsTen-minute inhalation of the yuzu scent significantly decreased salivary CgA. At 30 minutes after the inhalation period, the salivary CgA level further decreased. In addition, POMS revealed that inhalation of the aromatic yuzu oil significantly decreased total mood disturbance, a global measure of affective state, as well as four subscores of emotional symptoms (tension-anxiety, depression-dejection, anger-hostility, and confusion), as long as 30 minutes after the olfactory stimulation.
conclusionsYuzu's aromatic effects may alleviate negative emotional stress, which, at least in part, would contribute to the suppression of sympathetic nervous system activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.