Evidence map›Paper›PMID 24741601›Full record

SynthesisJournal of immunology research2014

Is vestibular neuritis an immune related vestibular neuropathy inducing vertigo?

A Greco, G F Macri, A Gallo, M Fusconi, A De Virgilio, G Pagliuca, C Marinelli, M de Vincentiis

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Journal of immunology research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 77 citations in OpenAlex.

  1. Corticosteroids versus vestibular rehabilitation in long-term outcomes in vestibular neuritis.Journal of vestibular research : equilibrium & orientation · 2018
    Trial
  2. Significance of Systemic Immune-Inflammation and Inflammatory Response Indices in Vestibular Neuritis.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. [A retrospective analysis of the clinical characteristics of 63 patients with vestibular neuritis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Article
  7. Review
  8. Lesion Location and Possible Etiology of Acute Unilateral Vestibulopathy.International journal of general medicine · 2025
    Article
  9. Article
  10. Article
  11. Prevalence of self-perceived audiovestibular symptoms in Egyptian COVID-19 patients.The Journal of the Egyptian Public Health Association · 2023
    Article
  12. Review
  13. Article
  14. New Onset Vertigo After COVID-19 Infection. A Case Report.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  15. Neuro-otological Symptoms: An Atypical Aspect of COVID-19 Disease.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. [Serum 25-hydroxyvitamin D expression and its correlation in patients with vestibular neuritis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

A GrecoOrgans of Sense Department, ENT Section, Policlinico "Umberto I" University of Rome "Sapienza", Lgo Valerio Bacigalupo 32 C, 00142 Rome, Italy.
G F MacriOrgans of Sense Department, ENT Section, Policlinico "Umberto I" University of Rome "Sapienza", Lgo Valerio Bacigalupo 32 C, 00142 Rome, Italy.
A GalloOrgans of Sense Department, ENT Section, Policlinico "Umberto I" University of Rome "Sapienza", Lgo Valerio Bacigalupo 32 C, 00142 Rome, Italy.
M FusconiOrgans of Sense Department, ENT Section, Policlinico "Umberto I" University of Rome "Sapienza", Lgo Valerio Bacigalupo 32 C, 00142 Rome, Italy.
A De VirgilioOrgans of Sense Department, ENT Section, Policlinico "Umberto I" University of Rome "Sapienza", Lgo Valerio Bacigalupo 32 C, 00142 Rome, Italy.
G PagliucaOrgans of Sense Department, ENT Section, Policlinico "Umberto I" University of Rome "Sapienza", Lgo Valerio Bacigalupo 32 C, 00142 Rome, Italy.
C MarinelliOrgans of Sense Department, ENT Section, Policlinico "Umberto I" University of Rome "Sapienza", Lgo Valerio Bacigalupo 32 C, 00142 Rome, Italy.
M de VincentiisOrgans of Sense Department, ENT Section, Policlinico "Umberto I" University of Rome "Sapienza", Lgo Valerio Bacigalupo 32 C, 00142 Rome, Italy.
Policlinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo review the current knowledge of the aetiology of vestibular neuritis including viral infections, vascular occlusion, and immunomediated mechanisms and to discuss the pathogenesis with relevance to pharmacotherapy. SYSTEMATIC REVIEW METHODOLOGY: Relevant publications on the aetiology and treatment of vestibular neuritis from 1909 to 2013 were analysed. RESULTS AND

conclusionsVestibular neuritis is the second most common cause of peripheral vestibular vertigo and is due to a sudden unilateral loss of vestibular function. Vestibular neuronitis is a disorder thought to represent the vestibular-nerve equivalent of sudden sensorineural hearing loss. Histopathological studies of patients who died from unrelated clinical problems have demonstrated degeneration of the superior vestibular nerve. The characteristic signs and symptoms include sudden and prolonged vertigo, the absence of auditory symptoms, and the absence of other neurological symptoms. The aetiology and pathogenesis of the condition remain unknown. Proposed theories of causation include viral infections, vascular occlusion, and immunomediated mechanisms. The management of vestibular neuritis involves symptomatic treatment with antivertiginous drugs, causal treatment with corticosteroids, and physical therapy. Antiviral agents did not improve the outcomes.

Indexed as

AnimalsHumansInfectionsVertigoVestibular NerveVestibular Neuronitis

Identifiers

PMID24741601
PMCPMC3987789
OpenAlexW1975513028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.