ArticleNorth American journal of medical sciences2014
Ovarian granulosa cell tumor: clinical features, treatment, outcome, and prognostic factors.
Article in North American journal of medical sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- The Prognostic Significance of Adjuvant Chemotherapy in Adult Ovarian Granulosa Cell Tumors: A Systematic Review and Meta-analysis.Cancer control : journal of the Moffitt Cancer CenterPooled it
- Identification of prognostic factors and construction of nomogram to predict cancer-specific survival for patients with ovarian granulosa cell tumors.Cancer reports (Hoboken, N.J.) · 2024Trial
- Stage IA and IC adult granulosa cell tumors: Clinical features, long-term outcomes and prognostic factors in a 333-patient cohort over three decades.International journal of clinical oncology · 2025Article
- The impact of hypoxia on the cellular phenotype and proteome of KGN cells.Reproduction & fertility · 2025Article
- CRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti-tumoral compounds.Molecular oncology · 2025Article
- Intraoperative Diagnosis: Imprint Cytology and Frozen Section in Ovarian Tumor, Averting Additional Surgery.Journal of pharmacy & bioallied sciences · 2024Article
- Clinical features and survival rate of patients with ovarian granulosa cell tumor in Iran; a 10-year retrospective study.BMC cancer · 2024Article
- Story of 20 Years of Triumph: A Case Report of Two Patients With Stage IV Granulosa Cell Tumor of the Ovary.Cureus · 2024Article
- A clinicopathological study about the epidemiology of granulosa cell tumors in Lebanon.BMC cancer · 2024Article
- Clinicopathological Features and Outcomes of Granulosa Cell Tumor of the Ovaries - A Retrospective Study.Cureus · 2023Article
- Adult-Type Ovarian Granulosa Cell Tumour: Treatment Outcomes From a Single-Institution Experience.Cureus · 2022Article
- Characterization of Ovarian Granulosa Cell Tumors using Magnetic Resonance Imaging.Medical research archives · 2022Article
- Non-Epithelial Ovarian Cancers: How Much Do We Really Know?International journal of environmental research and public health · 2022Review
- Article
- Clinical and paraclinical features, outcome, and prognosis of ovarian granulosa cell tumor: A retrospective study of 28 Vietnamese women.Rare tumors · 2022Article
- Coexistence of Ovarian Granulose Cell Tumor, Congenital Adrenal Hyperplasia, and Triple Translocation: Is a Consequence or Coincidence?Journal of gastrointestinal cancer · 2021Article
- FOXO1 mitigates the SMAD3/FOXL2Journal of translational medicine · 2021Article
- Mutant FOXL2Cancer research · 2020Article
- Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase-Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Type.Clinical cancer research : an official journal of the American Association for Cancer Research · 2020Article
- Multimodality imaging and genomics of granulosa cell tumors.Abdominal radiology (New York) · 2020Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGranulosa cell tumors are rare neoplasms characterized by long natural history and favorable prognosis.
aimsThe objective of this study was to determine the clinical presentation, treatment, outcome, and prognostic factors for patients of granulosa cell tumors. MATERIALS AND
methodsA retrospective analysis of 26 patients of granulosa cell tumor of ovary from 2002 to 2011 was carried out. The records of all patients were analyzed to determine clinical presentation, treatment, survival, and prognostic factors.
resultsThe median age of the patients was 50 years (range, 17-71 years). Abdominal pain was the most common presenting symptom. The median follow-up was 71.4 months (range, 21.6-149.9 months). The estimated 5 and 10 year overall survival (OS) was 84.6 and 72.5%, respectively. Event-free survival (EFS) was 76.5 and 52.9% at 5 and 10 years, respectively. Advanced stage was significant independent poor prognostic indicator for both OS and EFS.
conclusionMajority of the patients with granulosa cell tumors of the ovary present in early stage. Surgery is the primary treatment modality for granulosa cell tumors. Advanced stage and presence of residual disease were associated with inferior survival, but only prospective studies can ascertain their definite role.
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