ArticleEplasty2014
Debulking surgery for elephantiasis nostras with large ectatic podoplanin-negative lymphatic vessels in patients with lipo-lymphedema.
Article in Eplasty, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- [Differential diagnostics of lipedema and lymphedema : A practical guideline].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2018Guideline
- [Differential diagnostics of lipedema and lymphedema : A practical guideline].Zeitschrift fur Rheumatologie · 2018Guideline
- Outcomes of liposuction techniques for management of lipedema: a case series and narrative review.Annals of translational medicine · 2024Review
- Ketogenic Diet: A Nutritional Therapeutic Tool for Lipedema?Current obesity reports · 2023Review
- Lipedema-Pathogenesis, Diagnosis, and Treatment Options.Deutsches Arzteblatt international · 2020Review
- Lipedema: A Call to Action!Obesity (Silver Spring, Md.) · 2019Review
- Lipoedema is not lymphoedema: A review of current literature.International wound journal · 2018Review
- [Lipedema: up-to-date of a long forgotten disease].Wiener medizinische Wochenschrift (1946) · 2017Review
- Hereditary Lymphedema of the Leg - A Case Report.Open access Macedonian journal of medical sciences · 2017Article
- Lipedema: diagnostic and management challenges.International journal of women's health · 2016Review
- [Complex decongestive therapy].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2015Review
- Juxta-articular adiposis dolorosa (Dercum's disease type IV): report of four cases and treatment by dermolipectomy.Wiener medizinische Wochenschrift (1946) · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveElephantiasis nostras is a rare complication in advanced lipo-lymphedema. While lipedema can be treated by liposuction and lymphedema by decongestive lymphatic therapy, elephantiasis nostras may need debulking surgery.
methodsWe present 2 cases of advanced lipo-lymphedema complicated by elephantiasis nostras. After tumescent microcannular laser-assisted liposuction both patients underwent a debulking surgery with a modification of Auchincloss-Kim's technique. Histologic examination of the tissue specimen was performed.
resultsThe surgical treatment was well tolerated and primary healing was uneventful. After primary wound healing and ambulation of the patients, a delayed ulceration with lymphorrhea developed. It was treated by surgical necrectomy and vacuum-assisted closure leading to complete healing. Mobility of the leg was much improved. Histologic examination revealed massive ectatic lymphatic vessels nonreactive for podoplanin.
conclusionsDebulking surgery can be an adjuvant technique for elephantiasis nostras in advanced lipo-lymphedema. Although delayed postoperative wound healing problems were observed, necrectomy and vacuum-assisted closure achieved a complete healing. Histologic data suggest that the ectatic lymphatic vessels in these patients resemble finding in podoplanin knockout mice. The findings would explain the limitations of decongestive lymphatic therapy and tumescent liposuction in such patients and their predisposition to relapsing erysipelas.
Indexed as
Identifiers
24741382PMC3944717W58940996What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.