Evidence map›Paper›PMID 24741298›Full record

ArticleClinical interventions in aging2014

Long-term effects of antihypertensive medications on bone mineral density in men older than 55 years.

Kamil Serkan Ağaçayak, Sedat Güven, Mahmut Koparal, Nedim Güneş, Yusuf Atalay, Serhat Atılgan

Open access · goldAbstract read
In one paragraph

Article in Clinical interventions in aging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Potential cause affecting bone quality in Saudi Arabia: New insights.Journal of family medicine and primary care · 2021
    Article
  10. Article
  11. Article
  12. CaAging cell · 2019
    Article
  13. Review
  14. Two-year cortical and trabecular bone loss in CKD-5D: biochemical and clinical predictors.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Kamil Serkan AğaçayakDepartment of Oral and Maxillofacial Surgery, Turkey.
Sedat GüvenDepartment of Prosthodontics, School of Dentistry, University of Dicle, Diyarbakır, Turkey.
Mahmut KoparalDepartment of Oral and Maxillofacial Surgery, Turkey.
Nedim GüneşDepartment of Oral and Maxillofacial Surgery, Turkey.
Yusuf AtalayDepartment of Oral and Maxillofacial Surgery, School of Dentistry, University of Afyon Kocatepe, Afyon, Turkey.
Serhat AtılganDepartment of Oral and Maxillofacial Surgery, Turkey.
Afyon Kocatepe University · TRDicle University · TRNational Medical Research Center of Dentistry and Maxillofacial Surgery · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn this study, we investigated the effects of long-term antihypertensive treatment with calcium channel blockers or beta blockers on the bone mineral density of maxilla, as determined by cone-beam computed tomography (CBCT). MATERIAL AND

methodsThis retrospective study was conducted on CBCT images of men older than 55 years who had received different dental indications. Data were grouped into three categories according to the antihypertensive medication history of the patients: group A included patients who had been taking beta-blocker treatment for more than 5 years, group B included patients who had been taking calcium channel blocker treatment for more than 5 years, and the control group included patients who had never used any hypertensive medications before.

resultsStatistically significant differences were observed between the beta blocker and calcium channel blocker groups.

conclusionIn hypertension treatment, beta blockers may be preferred to calcium channel blockers in patients at high risk for osteoporosis and bone resorption.

Indexed as

Adrenergic beta-AntagonistsAntihypertensive AgentsBone DensityCalcium Channel BlockersCone-Beam Computed TomographyHumansHypertensionMaleMaxillaMiddle AgedRetrospective StudiesTime FactorsAdrenergic beta-AntagonistsAntihypertensive AgentsCalcium Channel Blockersbeta blockersbone mineral densitycalcium channel blockersCBCT

Identifiers

PMID24741298
PMCPMC3970919
OpenAlexW2097900242

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.