ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2014
Mapping the perceptual grain of the human retina.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
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Who cites it
65 citing papers in PubMed.
- Adaptive optics microperimetry and OCT images show preserved function and recovery of cone visibility in macular telangiectasia type 2 retinal lesions.Investigative ophthalmology & visual science · 2015Trial
- Repeatability of Foveal Sensitivity Measured Using Adaptive Optics Microperimetry.Translational vision science & technology · 2026Article
- How "Micro" Is Microperimetry? Characterizing the Effect of Fundus Tracking on the Psychometric Function.Investigative ophthalmology & visual science · 2026Article
- Physiological basis of resolution acuity in vision.Nature communications · 2026Article
- Roadmap on advances in visual and physiological optics.Journal of optics (2010) · 2025Review
- Integrated fixation and stimulus channel for adaptive optics ophthalmoscopy.Biomedical optics express · 2025Article
- Local variations in L/M ratio influence the detection and color naming of small spots.Journal of vision · 2025Article
- Local variations in L/M ratio influence the detection and color naming of small spots.bioRxiv : the preprint server for biology · 2025Article
- Asymmetric activation of retinal ON and OFF pathways by AOSLO raster-scanned visual stimuli.Biomedical optics express · 2025Article
- Novel color via stimulation of individual photoreceptors at population scale.Science advances · 2025Article
- Fixational eye movements as active sensation for high visual acuity.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Unique yellow shifts for small and brief stimuli in the central retina.Journal of vision · 2024Article
- Boosting 2-photon vision with adaptive optics.Journal of vision · 2023Article
- It's not easy seeing green: The veridical perception of small spots.Journal of vision · 2023Article
- Twenty-five years of clinical applications using adaptive optics ophthalmoscopy [Invited].Biomedical optics express · 2023Review
- Repeatability and reciprocity of the cone optoretinogram.Biomedical optics express · 2022Article
- Retinal imaging using adaptive optics optical coherence tomography with fast and accurate real-time tracking.Biomedical optics express · 2022Article
- Assessment of binocular fixational eye movements including cyclotorsion with split-field binocular scanning laser ophthalmoscopy.Journal of vision · 2022Article
- Short-term Assessment of Subfoveal Injection of Adeno-Associated Virus-Mediated hCHM Gene Augmentation in Choroideremia Using Adaptive Optics Ophthalmoscopy.JAMA ophthalmology · 2022Article
- Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
In humans, experimental access to single sensory receptors is difficult to achieve, yet it is crucial for learning how the signals arising from each receptor are transformed into perception. By combining adaptive optics microstimulation with high-speed eye tracking, we show that retinal function can be probed at the level of the individual cone photoreceptor in living eyes. Classical psychometric functions were obtained from cone-sized microstimuli targeted to single photoreceptors. Revealed psychophysically, the cone mosaic also manifests a variable sensitivity to light across its surface that accords with a simple model of cone light capture. Because this microscopic grain of vision could be detected on the perceptual level, it suggests that photoreceptors can act individually to shape perception, if the normally suboptimal relay of light by the eye's optics is corrected. Thus the precise arrangement of cones and the exact placement of stimuli onto those cones create the initial retinal limits on signals mediating spatial vision.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.