ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2014
Environmental acoustic enrichment promotes recovery from developmentally degraded auditory cortical processing.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 59 citations in OpenAlex.
- Music enrichment programs improve the neural encoding of speech in at-risk children.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Trial
- Age-Dependent Auditory Plasticity: Critical Periods in Subcortical and Cortical Encoding.Journal of audiology & otology · 2026Review
- Complex Three-Dimensional Rearing Environments Amplify Compensatory Plasticity Following Early Blindness.eNeuro · 2026Article
- Article
- Revealing Pathological Auditory Central Inhibition in Tinnitus Using Cortical Auditory Evoked Potentials Responses to Contralateral Acoustic Stimulation.Brain and behavior · 2025Article
- Effect of Sound Amplification on Central Auditory Plasticity: Endbulb of Held as a Substrate.Brain sciences · 2025Article
- Environmental enrichment reverses noise induced impairments in learning and memory associated with the hippocampus in female rats.Scientific reports · 2025Article
- Pairing with Enriched Sound Exposure Restores Auditory Processing Degraded by an Antidepressant.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Developmental Exposure to Bisphenol a Degrades Auditory Cortical Processing in Rats.Neuroscience bulletin · 2022Article
- Environmental noise degrades hippocampus-related learning and memory.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Acoustically Enriched Environment during the Critical Period of Postnatal Development Positively Modulates Gap Detection and Frequency Discrimination Abilities in Adult Rats.Neural plasticity · 2021Article
- BDNF deficiency and enriched environment treatment affect neurotransmitter gene expression differently across ages.Journal of neurochemistry · 2020Article
- Effects of Non-traumatic Noise and Conductive Hearing Loss on Auditory System Function.Neuroscience · 2019Review
- Synaptic plasticity/dysplasticity, process memory and item memory in rodent models of mental dysfunction.Schizophrenia research · 2019Review
- Effect of acoustic stimuli in patients with disorders of consciousness: a quantitative electroencephalography study.Neural regeneration research · 2018Article
- Induction of prolonged natural lifespans in mice exposed to acoustic environmental enrichment.Scientific reports · 2018Article
- Brief Stimulus Exposure Fully Remediates Temporal Processing Deficits Induced by Early Hearing Loss.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Noise Trauma-Induced Behavioral Gap Detection Deficits Correlate with Reorganization of Excitatory and Inhibitory Local Circuits in the Inferior Colliculus and Are Prevented by Acoustic Enrichment.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Positive impacts of early auditory training on cortical processing at an older age.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Benefits of Stimulus Exposure: Developmental Learning Independent of Task Performance.Frontiers in neuroscience · 2016Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
It has previously been shown that environmental enrichment can enhance structural plasticity in the brain and thereby improve cognitive and behavioral function. In this study, we reared developmentally noise-exposed rats in an acoustic-enriched environment for ∼4 weeks to investigate whether or not enrichment could restore developmentally degraded behavioral and neuronal processing of sound frequency. We found that noise-exposed rats had significantly elevated sound frequency discrimination thresholds compared with age-matched naive rats. Environmental acoustic enrichment nearly restored to normal the behavioral deficit resulting from early disrupted acoustic inputs. Signs of both degraded frequency selectivity of neurons as measured by the bandwidth of frequency tuning curves and decreased long-term potentiation of field potentials recorded in the primary auditory cortex of these noise-exposed rats also were reversed partially. The observed behavioral and physiological effects induced by enrichment were accompanied by recovery of cortical expressions of certain NMDA and GABAA receptor subunits and brain-derived neurotrophic factor. These studies in a rodent model show that environmental acoustic enrichment promotes recovery from early noise-induced auditory cortical dysfunction and indicate a therapeutic potential of this noninvasive approach for normalizing neurological function from pathologies that cause hearing and associated language impairments in older children and adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.