ReviewCurrent opinion in pediatrics2014
Recent evidence on the management of bronchiolitis.
Review in Current opinion in pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- The cost-effectiveness of hypertonic saline inhalations for infant bronchiolitis: a decision analysis.World journal of pediatrics : WJP · 2018Pooled it
- Hypertonic saline (HS) for acute bronchiolitis: Systematic review and meta-analysis.BMC pulmonary medicine · 2015Pooled it
- Article
- Management of Hospitalized Respiratory Syncytial Virus Bronchiolitis in the Pediatric Ward in Spain: Assessing the Impact of a New Clinical Practice Protocol.Paediatric drugs · 2022Article
- Nine Seasons of a Bronchiolitis Observation Unit and Home Oxygen Therapy Protocol.Journal of hospital medicine · 2021Article
- Hyponatremia in children with respiratory infections: a cross-sectional analysis of a cohort of 3938 patients.Scientific reports · 2018Article
- Multicenter Study of Albuterol Use Among Infants Hospitalized with Bronchiolitis.The western journal of emergency medicine · 2018Observational
- [Expression of vascular intercellular adhesion molecule-1 and its significance in children with bronchiolitis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2018Article
- Marked variability observed in inpatient management of bronchiolitis in three Finnish hospitals.Acta paediatrica (Oslo, Norway : 1992) · 2017Article
- Article
- Virus Type and Genomic Load in Acute Bronchiolitis: Severity and Treatment Response With Inhaled Adrenaline.The Journal of infectious diseases · 2016Article
- Three-weekly doses of azithromycin for indigenous infants hospitalized with bronchiolitis: a multicentre, randomized, placebo-controlled trial.Frontiers in pediatrics · 2015Article
- Bronchiolitis: Recommendations for diagnosis, monitoring and management of children one to 24 months of age.Paediatrics & child health · 2014Article
- Bronchiolitis in children - do we choose wisely?Developmental period medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
purpose of reviewBronchiolitis is a common condition in children less than 2 years of age and is a leading cause of infant hospitalization. Although there is significant variability in testing and treatment of children with bronchiolitis, diagnostic testing rarely improves care, and no currently available pharmacologic options have been proven to provide meaningful benefits or improve outcomes. RECENT
findingsBeta-agonists continue to be used frequently despite evidence that they do not reduce hospital admissions or length of stay. In general, therapies initially considered promising were subsequently proven ineffective, a pattern seen in studies on corticosteroids, and more recently with nebulized racemic epinephrine and hypertonic saline. Recent research has improved our understanding of the viral epidemiology of bronchiolitis, with increasing recognition of viruses other than respiratory syncytial virus and better awareness of the role of viral coinfections. How these findings will translate into improved outcomes remains uncertain. SUMMARY: Much of the emphasis of the last few decades of bronchiolitis clinical care and research has centered on the identification and testing of novel therapies. Future quality improvement efforts should focus more on the limitation of unnecessary testing and treatments. Future research should include identification of subgroups of children with bronchiolitis that may benefit from focused clinical interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.