ArticleBiophysical journal2014
Fast label-free cytoskeletal network imaging in living mammalian cells.
Article in Biophysical journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- On the potential of microtubules for scalable quantum computation.European physical journal plus · 2025Review
- Quantitative phase microscopies: accuracy comparison.Light, science & applications · 2024Review
- Long-term zinc treatment alters the mechanical properties and metabolism of prostate cancer cells.Cancer cell international · 2024Article
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- Single-shot quantitative phase-fluorescence imaging using cross-grating wavefront microscopy.Scientific reports · 2024Article
- Imaging actin organisation and dynamics in 3D.Journal of cell science · 2024Article
- How great thou ART: biomechanical properties of oocytes and embryos as indicators of quality in assisted reproductive technologies.Frontiers in cell and developmental biology · 2024Review
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- Multimodal image reconstruction from tomographic diffraction microscopy data.Journal of microscopy · 2022Article
- On Some Current Challenges in High-Resolution Optical Bioimaging.ACS photonics · 2022Review
- Spontaneous circulation of active microtubules confined by optical traps.Journal of biological physics · 2021Article
- Spatial light interference microscopy: principle and applications to biomedicine.Advances in optics and photonics · 2021Article
- Label-free multimodal quantitative imaging flow assay for intrathrombus formation in vitro.Biophysical journal · 2021Article
- PARC: ultrafast and accurate clustering of phenotypic data of millions of single cells.Bioinformatics (Oxford, England) · 2020Article
- Article
- Mapping of real-time morphological changes in the neuronal cytoskeleton with label-free wide-field second-harmonic imaging: a case study of nocodazole.Neurophotonics · 2019Article
- A Toolbox for Organelle Mechanobiology Research-Current Needs and Challenges.Micromachines · 2019Article
- Tubulin Polarizability in Aqueous Suspensions.ACS omega · 2019Article
- Self-interference 3D super-resolution microscopy for deep tissue investigations.Nature methods · 2018Article
- Three-dimensional nanometre localization of nanoparticles to enhance super-resolution microscopy.Nature communications · 2015Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present a full-field technique that allows label-free cytoskeletal network imaging inside living cells. This noninvasive technique allows monitoring of the cytoskeleton dynamics as well as interactions between the latter and organelles on any timescale. It is based on high-resolution quantitative phase imaging (modified Quadriwave lateral shearing interferometry) and can be directly implemented using any optical microscope without modification. We demonstrate the capability of our setup on fixed and living Chinese hamster ovary cells, showing the cytoskeleton dynamics in lamellipodia during protrusion and mitochondria displacement along the cytoskeletal network. In addition, using the quantitative function of the technique, along with simulation tools, we determined the refractive index of a single tubulin microtubule to be ntubu=2.36±0.6 at λ=527 nm.
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