ArticleACS nano2014
Biologically derived soft conducting hydrogels using heparin-doped polymer networks.
Article in ACS nano, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed.
- Boosting hydrogel conductivity via water-dispersible conducting polymers for injectable bioelectronics.Nature communications · 2025Article
- Self-Doped and Biodegradable Glycosaminoglycan-PEDOT Conductive Hydrogels Facilitate Electrical Pacing of iPSC-Derived Cardiomyocytes.Advanced healthcare materials · 2025Article
- Electrically conductive "SMART" hydrogels for on-demand drug delivery.Asian journal of pharmaceutical sciences · 2025Review
- Recent Advances in Bioinspired Hydrogels: Materials, Devices, and Biosignal Computing.ACS biomaterials science & engineering · 2023Review
- Recent Advances and Progress of Conducting Polymer-Based Hydrogels in Strain Sensor Applications.Gels (Basel, Switzerland) · 2022Review
- Electronically Conductive Hydrogels by in Situ Polymerization of a Water-Soluble EDOT-Derived Monomer.Advanced engineering materials · 2022Article
- A short review on the synthesis and advance applications of polyaniline hydrogels.RSC advances · 2022Review
- Conductive Gels: Properties and Applications of Nanoelectronics.Nanoscale research letters · 2022Review
- Towards conductive hydrogels in e-skins: a review on rational design and recent developments.RSC advances · 2021Review
- Three-Dimensional Printable Conductive Semi-Interpenetrating Polymer Network Hydrogel for Neural Tissue Applications.Biomacromolecules · 2021Article
- Electrically Conductive and 3D-Printable Oxidized Alginate-Gelatin Polypyrrole:PSS Hydrogels for Tissue Engineering.Advanced healthcare materials · 2021Article
- 3D Printing of Polycaprolactone-Polyaniline Electroactive Scaffolds for Bone Tissue Engineering.Materials (Basel, Switzerland) · 2020Article
- Cytocompatible, Injectable, and Electroconductive Soft Adhesives with Hybrid Covalent/Noncovalent Dynamic Network.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019Article
- Conducting Polymers, Hydrogels and Their Composites: Preparation, Properties and Bioapplications.Polymers · 2019Review
- A Self-Healing, All-Organic, Conducting, Composite Peptide Hydrogel as Pressure Sensor and Electrogenic Cell Soft Substrate.ACS nano · 2019Article
- Conducting Polymers for Tissue Engineering.Biomacromolecules · 2018Review
- Surface-immobilized and self-shaped DNA hydrogels and their application in biosensing.Chemical science · 2018Article
- A Novel Antibacterial Membrane Electrode Based on Bacterial Cellulose/Polyaniline/AgNOIEEE journal of translational engineering in health and medicine · 2018Article
- A robust, highly stretchable supramolecular polymer conductive hydrogel with self-healability and thermo-processability.Scientific reports · 2017Article
- Electroconductive Hydrogel Based on Functional Poly(Ethylenedioxy Thiophene).Chemistry of materials : a publication of the American Chemical Society · 2016Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
The emergence of flexible and stretchable electronic components expands the range of applications of electronic devices. Flexible devices are ideally suited for electronic biointerfaces because of mechanically permissive structures that conform to curvilinear structures found in native tissue. Most electronic materials used in these applications exhibit elastic moduli on the order of 0.1-1 MPa. However, many electronically excitable tissues exhibit elasticities in the range of 1-10 kPa, several orders of magnitude smaller than existing components used in flexible devices. This work describes the use of biologically derived heparins as scaffold materials for fabricating networks with hybrid electronic/ionic conductivity and ultracompliant mechanical properties. Photo-cross-linkable heparin-methacrylate hydrogels serve as templates to control the microstructure and doping of in situ polymerized polyaniline structures. Macroscopic heparin-doped polyaniline hydrogel dual networks exhibit impedances as low as Z = 4.17 Ω at 1 kHz and storage moduli of G' = 900 ± 100 Pa. The conductivity of heparin/polyaniline networks depends on the oxidation state and microstructure of secondary polyaniline networks. Furthermore, heparin/polyaniline networks support the attachment, proliferation, and differentiation of murine myoblasts without any surface treatments. Taken together, these results suggest that heparin/polyaniline hydrogel networks exhibit suitable physical properties as an electronically active biointerface material that can match the mechanical properties of soft tissues composed of excitable cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.