ArticlePlant, cell & environment2015
Four Arabidopsis AREB/ABF transcription factors function predominantly in gene expression downstream of SnRK2 kinases in abscisic acid signalling in response to osmotic stress.
Article in Plant, cell & environment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 298 papers, 1 of them a synthesis that pooled it.
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298 citing papers in PubMed, 1 synthesis or guideline pooled it, 614 citations in OpenAlex.
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- SnRK2.4 and SnRK2.10 redundantly control developmental leaf senescence by sustaining ABA production and signaling.Plant physiology · 2026Article
- Integration of Spatiotemporal Multi-Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome-Mediated Stress Adaptation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Integrative transcriptional regulatory networks governing cereal root responses to heavy metals and drought.Plant cell reports · 2026Review
- Genome-Wide Survey and Expression Profiling of bZIP Transcription Factors inInternational journal of molecular sciences · 2026Article
- Genome-Wide Identification and Expression Profiling of theInternational journal of molecular sciences · 2026Article
- Genome-wide identification of the SnRK gene family in willow and expression analysis under abiotic stress.BMC plant biology · 2026Article
- The ABA receptor NtPYL6 promotes flavonol biosynthesis to enhance tobacco resistance to UV-B.Plant physiology · 2026Article
- Integrated transcriptomic and metabolomic analyses reveal melatonin-mediated drought response in red raspberry at the squaring stage.BMC plant biology · 2026Article
- Genome-wide identification and functional characterization of ABA and salt stress responsive AITRs transcriptional repressors genes in sweet potato (Ipomoea batatas).BMC plant biology · 2026Article
- Classical Phytohormones and Peptide Plant Hormones in Abiotic Stress Tolerance: Crosstalk, Physiological Integration, and Crop Improvement.Plants (Basel, Switzerland) · 2026Review
- Identification ofPlants (Basel, Switzerland) · 2026Article
- Research progress on the regulatory mechanisms of the PSY promoter.Transgenic research · 2026Review
- Differential splicing fine-tunes guard cell gene expression and is required for drought tolerance in Arabidopsis thaliana.The Plant journal : for cell and molecular biology · 2026Article
- Brassinosteroid Potentiates Cold-Induced Transcriptome-Metabolome Reprogramming in Tea Plant Leaves: An Integrated Multi-Omics Landscape.International journal of molecular sciences · 2026Article
- AtAUGs Suppress the Expression of PP2C Genes to Redundantly Regulate ABA Responses in Arabidopsis.Plants (Basel, Switzerland) · 2026Article
- Genome-wide identification of the ATL gene family and their expression analysis in sweetpotato and its two diploid relatives.BMC plant biology · 2026Article
238 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Under osmotic stress conditions such as drought and high salinity, the plant hormone abscisic acid (ABA) plays important roles in stress-responsive gene expression mainly through three bZIP transcription factors, AREB1/ABF2, AREB2/ABF4 and ABF3, which are activated by SNF1-related kinase 2s (SnRK2s) such as SRK2D/SnRK2.2, SRK2E/SnRK2.6 and SRK2I/SnRK2.3 (SRK2D/E/I). However, since the three AREB/ABFs are crucial, but not exclusive, for the SnRK2-mediated gene expression, transcriptional pathways governed by SRK2D/E/I are not fully understood. Here, we show that a bZIP transcription factor, ABF1, is a functional homolog of AREB1, AREB2 and ABF3 in ABA-dependent gene expression in Arabidopsis. Despite lower expression levels of ABF1 than those of the three AREB/ABFs, the areb1 areb2 abf3 abf1 mutant plants displayed increased sensitivity to drought and decreased sensitivity to ABA in primary root growth compared with the areb1 areb2 abf3 mutant. Genome-wide transcriptome analyses revealed that expression of downstream genes of SRK2D/E/I, which include many genes functioning in osmotic stress responses and tolerance such as transcription factors and LEA proteins, was mostly impaired in the quadruple mutant. Thus, these results indicate that the four AREB/ABFs are the predominant transcription factors downstream of SRK2D/E/I in ABA signalling in response to osmotic stress during vegetative growth.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.