ArticleBiomicrofluidics2014
Diffraction-limited ultrasensitive molecular nano-arrays with singular nano-cone scattering.
Article in Biomicrofluidics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Electrodeposited magnetic nanoporous membrane for high-yield and high-throughput immunocapture of extracellular vesicles and lipoproteins.Communications biology · 2022Article
- Current Technologies and Recent Developments for Screening of HPV-Associated Cervical and Oropharyngeal Cancers.Cancers · 2016Review
- Future microfluidic and nanofluidic modular platforms for nucleic acid liquid biopsy in precision medicine.Biomicrofluidics · 2016Review
- A bead-based fluorescence immunosensing technique enabled by the integration of Förster resonance energy transfer and optoelectrokinetic concentration.Biomicrofluidics · 2016Article
- Alternating current electrohydrodynamics in microsystems: Pushing biomolecules and cells around on surfaces.Biomicrofluidics · 2015Review
- Gold coated optical fibers as three-dimensional electrodes for microfluidic enzymatic biofuel cells: Toward geometrically enhanced performance.Biomicrofluidics · 2015Article
- Numerical simulation on the opto-electro-kinetic patterning for rapid concentration of particles in a microchannel.Biomicrofluidics · 2015Article
- Smartphone-interfaced lab-on-a-chip devices for field-deployable enzyme-linked immunosorbent assay.Biomicrofluidics · 2014Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Large-library fluorescent molecular arrays remain limited in sensitivity (1 × 10(6) molecules) and dynamic range due to background auto-fluorescence and scattering noise within a large (20-100 μm) fluorescent spot. We report an easily fabricated silica nano-cone array platform, with a detection limit of 100 molecules and a dynamic range that spans 6 decades, due to point (10 nm to 1 μm) illumination of preferentially absorbed tagged targets by singular scattering off wedged cones. Its fluorescent spot reaches diffraction-limited submicron dimensions, which are 10(4) times smaller in area than conventional microarrays, with comparable reduction in detection limit and amplification of dynamic range.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.