ReviewCancer informatics2014
Nonlinear optical microscopy signal processing strategies in cancer.
Review in Cancer informatics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Influences of Orally Taken Carotenoid-Rich Curly Kale Extract on Collagen I/Elastin Index of the Skin.Nutrients · 2017Trial
- Quantitative second harmonic generation microscopy for characterizing collagen remodeling in papillary thyroid carcinoma.Journal of biomedical optics · 2026Article
- Quantitative image analysis of the extracellular matrix of esophageal squamous cell carcinoma and high grade dysplasia via two-photon microscopy.Scientific reports · 2025Article
- Development and validation of a radiomics-based nomogram for predicting pathological grade of upper urinary tract urothelial carcinoma.BMC cancer · 2024Article
- A radiomics-based interpretable model to predict the pathological grade of pancreatic neuroendocrine tumors.European radiology · 2024Article
- SLAM medical imaging enabled by pre-chirp and gain jointly managed Yb-fiber laser.Biomedical optics express · 2024Article
- A computed tomography urography-based machine learning model for predicting preoperative pathological grade of upper urinary tract urothelial carcinoma.Cancer medicine · 2024Article
- Imaging of colorectal adenomas with pseudoinvasion and malignant polyps using two-photon excitation microscopy.Frontiers in oncology · 2024Article
- Two-photon images reveal unique texture features for label-free identification of ovarian cancer peritoneal metastases.Biomedical optics express · 2019Article
- Surgical preparations, labeling strategies, and optical techniques for cell-resolved, in vivo imaging in the mouse spinal cord.Experimental neurology · 2019Review
- Quantitative second harmonic generation microscopy for the structural characterization of capsular collagen in thyroid neoplasms.Biomedical optics express · 2018Article
- Epithelial Ovarian Cancer Diagnosis of Second-Harmonic Generation Images: A Semiautomatic Collagen Fibers Quantification Protocol.Cancer informatics · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This work reviews the most relevant present-day processing methods used to improve the accuracy of multimodal nonlinear images in the detection of epithelial cancer and the supporting stroma. Special emphasis has been placed on methods of non linear optical (NLO) microscopy image processing such as: second harmonic to autofluorescence ageing index of dermis (SAAID), tumor-associated collagen signatures (TACS), fast Fourier transform (FFT) analysis, and gray level co-occurrence matrix (GLCM)-based methods. These strategies are presented as a set of potential valuable diagnostic tools for early cancer detection. It may be proposed that the combination of NLO microscopy and informatics based image analysis approaches described in this review (all carried out on free software) may represent a powerful tool to investigate collagen organization and remodeling of extracellular matrix in carcinogenesis processes.
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