ArticleThe Journal of infectious diseases2014
Estimation of recent and long-term malaria transmission in a population by antibody testing to multiple Plasmodium falciparum antigens.
Article in The Journal of infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 51 papers.
What it found
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Who cites it
51 citing papers in PubMed.
- Reconstruction of historical malaria transmission in Senegal using multiplex serocatalytic models.PLoS computational biology · 2026Article
- Understanding the Epidemiology of Malaria in Zanzibar Through Molecular and Serological Analysis of Samples Collected During Reactive Case Detection.Open forum infectious diseases · 2026Article
- A flexible class of latent variable models for the analysis of antibody response data.Biostatistics (Oxford, England) · 2026Article
- Principal component analysis of the Serological response to Plasmodium Falciparum using a Multiplex bead-based assay in Nigeria.Scientific reports · 2024Article
- Article
- Geospatial analysis of Plasmodium falciparum serological indicators: school versus community sampling in a low-transmission malaria setting.BMC medicine · 2024Article
- Accumulation of Neutrophil Phagocytic Antibody Features Tracks With Naturally Acquired Immunity Against Malaria in Children.The Journal of infectious diseases · 2023Article
- Serology reveals micro-differences inFrontiers in parasitology · 2023Article
- Sensitivity and specificity for malaria classification of febrile persons by rapid diagnostic test, microscopy, parasite DNA, histidine-rich protein 2, and IgG: Dakar, Senegal 2015.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022Article
- Etramp5 as a useful serological marker in children to assess the immediate effects of mass drug campaigns for malaria.BMC infectious diseases · 2022Article
- Spatial Distribution of Plasmodium falciparum and Plasmodium vivax in Northern Ethiopia by Microscopic, Rapid Diagnostic Test, Laboratory Antibody, and Antigen Data.The Journal of infectious diseases · 2022Article
- Article
- Distinct kinetics of antibodies to 111 Plasmodium falciparum proteins identifies markers of recent malaria exposure.Nature communications · 2022Article
- Antibody dynamics in children with first or repeatFrontiers in medicine · 2022Article
- Spatial, environmental, and individual associations withFrontiers in cellular and infection microbiology · 2022Article
- Framework for Characterizing Longitudinal Antibody Response in Children AfterFrontiers in immunology · 2021Article
- Antibody Profiles toThe American journal of tropical medicine and hygiene · 2020Article
- Antibody Correlates of Protection from ClinicalThe American journal of tropical medicine and hygiene · 2020Review
- Combination of Serological, Antigen Detection, and DNA Data for Plasmodium falciparum Provides Robust Geospatial Estimates for Malaria Transmission in Haiti.Scientific reports · 2020Article
- Screening for malaria antigen and anti-malarial IgG antibody in forcibly-displaced Myanmar nationals: Cox's Bazar district, Bangladesh, 2018.Malaria journal · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
Abstract
backgroundTools that estimate recent and long-term malaria transmission in a population would be highly useful for malaria elimination programs.
methodsThe prevalence of antibodies to 11 Plasmodium falciparum antigens was assessed by cytometric bead assay or enzyme-linked immunosorbent assay in 1000 people in a highland area of Kenya over 14 months, during a period of interrupted malaria transmission.
resultsAntibodies differed by antigen in acquisition with age: rapid (>80% antibody positive by age 20 years, 5 antigens), moderate (>40% positive by age 20 years, 3 antigens), or slow (<40% positive by age 20 years, 3 antigens). Antibody seroreversion rates in the 14 months between samples decreased with age rapidly (7 antigens), slowly (3 antigens), or remained high at all ages (schizont extract). Estimated antibody half-lives in individuals >10 years of age were long (40 to >80 years) for 5 antigens, moderate (5-20 years) for 3 antigens, and short (<1 year) for 3 antigens.
conclusionsAntibodies to P. falciparum antigens in malaria-endemic areas vary by age, antigen, and time since last exposure to P. falciparum. Multiplex P. falciparum antibody testing could provide estimates of long-term and recent malaria transmission and potentially of a population's susceptibility to future clinical malaria.
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