ArticleThe Journal of experimental biology2014
Olfactory learning and memory in the disease vector mosquito Aedes aegypti.
Article in The Journal of experimental biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 68 citations in OpenAlex.
- The brain of the female Anopheles gambiae mosquito at spatial and single-cell resolution.Nature communications · 2026Article
- Commercial permethrin elicits chemoreceptive responses on different Anopheles gambiae sensory appendages.Pest management science · 2026Article
- For your eyes too: a new set of images of biological materials from the scientific commissioning of the MOGNO beamline at Sirius.Journal of synchrotron radiation · 2026Article
- AgamOBP1-Directed Discovery of Repellents to Control the Spread of Mosquito-Borne Diseases.ChemMedChem · 2025Article
- Article
- The potential impacts of vector host species fidelity on zoonotic arbovirus transmission.PLoS neglected tropical diseases · 2025Article
- Dengue-mediated changes in the vectorial capacity of Aedes aegypti (Diptera: Culicidae): manipulation of transmission or infection by-product?Journal of medical entomology · 2025Review
- Conducting an Analysis of Mosquito Flight Behaviors in a Wind Tunnel.Cold Spring Harbor protocols · 2024Article
- Hydrophobic solution functions as a multifaceted mosquito repellent by enhancing chemical transfer, altering object tracking, and forming aversive memory.Scientific reports · 2024Article
- Effect of Temperature on Mosquito Olfaction.Integrative and comparative biology · 2023Article
- Effect of temperature on mosquito olfaction.bioRxiv : the preprint server for biology · 2023Article
- Limited Effect of Ground Floor Fogging on Mosquito Distribution in High-Rise Condominia.EcoHealth · 2023Article
- Biology and Behaviour ofViruses · 2023Review
- Neuromodulation and differential learning across mosquito species.Proceedings. Biological sciences · 2023Article
- Article
- Human attractive cues and mosquito host-seeking behavior.Trends in parasitology · 2022Review
- Standardised bioassays reveal that mosquitoes learn to avoid compounds used in chemical vector control after a single sub-lethal exposure.Scientific reports · 2022Article
- Landing mosquitoes bounce when engaging a substrate.Scientific reports · 2020Article
- Aversive conditioning in the tardigrade, Dactylobiotus dispar.Journal of experimental psychology. Animal learning and cognition · 2019Article
- Visual-Olfactory Integration in the Human Disease Vector Mosquito Aedes aegypti.Current biology : CB · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Olfactory learning in blood-feeding insects, such as mosquitoes, could play an important role in host preference and disease transmission. However, standardised protocols allowing testing of their learning abilities are currently lacking, and how different olfactory stimuli are learned by these insects remains unknown. Using a Pavlovian conditioning paradigm, we trained individuals and groups of Aedes aegypti mosquitoes to associate an odorant conditioned stimulus (CS) with a blood-reinforced thermal stimulus (unconditioned stimulus; US). Results showed, first, that mosquitoes could learn the association between L-lactic acid and the US, and retained the association for at least 24 h. Second, the success of olfactory conditioning was dependent upon the CS--some odorants that elicited indifferent responses in naïve mosquitoes, such as L-lactic acid and 1-octen-3-ol, were readily learned, whereas others went from aversive to attractive after training (Z-3-hexen-1-ol) or were untrainable (β-myrcene and benzyl alcohol). Third, we examined whether mosquitoes' ability to learn could interfere with the action of the insect repellent DEET. Results demonstrated that pre-exposure and the presence of DEET in the CS reduced the aversive effects of DEET. Last, the nature of the formed memories was explored. Experiments using cold-shock treatments within the first 6 h post-training (for testing anaesthesia-resistant memory) and a protein synthesis inhibitor (cycloheximide; to disrupt the formation of long-term memory) both affected mosquitoes' performances. Together, these results show that learning is a crucial component in odour responses in A. aegypti, and provide the first evidence for the functional role of different memory traces in these responses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.