Evidence map›Paper›PMID 24737730›Full record

ArticleAnatomical record (Hoboken, N.J. : 2007)2014

Variation in timing, duration, intensity, and direction of adolescent growth in the mandible, maxilla, and cranial base: the Fels longitudinal study.

Ramzi W Nahhas, Manish Valiathan, Richard J Sherwood

Abstract read
In one paragraph

Article in Anatomical record (Hoboken, N.J. : 2007), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Craniofacial growth percentile curves: A clinical tool from the Craniofacial Growth Consortium Study.American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics · 2026
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  9. [Clinical dilemma and indication selection of restoration for permanent tooth defects in adolescents].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025
    Review
  10. Review
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  14. Effects of endocrine disorders on maxillary and mandibular growth in Colombian children and adolescents: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024
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  20. Estimating Craniofacial Growth Cessation: Comparison of Asymptote- and Rate-Based Methods.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ramzi W NahhasDivision of Morphological Sciences and Biostatistics, Lifespan Health Research Center, Department of Community Health, Boonshoft School of Medicine, Wright State University, Dayton, Ohio.
Manish Valiathan
Richard J Sherwood

Funding

SUBCUTANEOUS FAT, BLOOD LIPIDS AND SUBSEQUENT OUTCOMER01HD012252 · NICHD · WRIGHT STATE UNIVERSITY · PI CZERWINSKI, STEFAN A. · 1985 to 2014
$17.3M
GENETIC ARCHITECTURE OF THE HUMAN CRANIOFACIAL COMPLEXR01DE016692 · NIDCR · WRIGHT STATE UNIVERSITY · PI SHERWOOD, RICHARD J · 2005 to 2008
$1.2M
Longitudinal Modeling of Craniofacial Growth TrajectoriesR03DE021435 · NIDCR · WRIGHT STATE UNIVERSITY · PI NAHHAS, RAMZI WILLIAM · 2011 to 2012
$277k
NICHD NIH HHS R01 HD012252NIDCR NIH HHS DE016692NIDCR NIH HHS DE021435NIDCR NIH HHS R01 DE016692NIDCR NIH HHS R03 DE021435
6 · The paper itself

Abstract

There is considerable individual variation in the timing, duration, and intensity of growth that occurs in the craniofacial complex during childhood and adolescence. The purpose of this article is to describe the extent of this variation between traits and between individuals within the Fels Longitudinal Study (FLS). Polynomial multilevel models were used to estimate the ages of onset, peak velocity, and cessation of adolescent growth, the time between these ages, the amount of growth between these ages, and peak velocity. This was done at both the group and individual levels for standard cephalometric measurements of the lengths of the mandible, maxilla, and cranial base, the gonial angle, and the saddle angle. Data are from 293 untreated boys and girls age 4-24 years in the FLS. The timing of the adolescent growth spurt was, in general, not significantly different between the mandible and the maxilla, with each having an earlier age of onset, later age of peak velocity, and later age of cessation of growth as compared to the cranial base length. Compared to lengths, angles had in general later ages of onset, peak velocity, and cessation of growth. Accurate characterization of the ontogenetic trajectories of the traits in the craniofacial complex is critical for both clinicians seeking to optimize treatment timing and anatomists interested in examining heterochrony.

Indexed as

Adolescent DevelopmentModels, StatisticalAdolescentChildChild, PreschoolFemaleHumansLongitudinal StudiesMaleMandibleMaxillaSkull BaseYoung Adultcraniofacialdevelopmentmathematical modelingmaturationmultilevel modelorthodonticspuberty

Identifiers

PMID24737730
PMCPMC4103980

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.