Evidence map›Paper›PMID 24737299›Full record

ArticleInternational urogynecology journal2014

The length of anterior vaginal wall exposed to external pressure on maximal straining MRI: relationship to urogenital hiatus diameter, and apical and bladder location.

Aisha Yousuf, Luyun Chen, Kindra Larson, James A Ashton-Miller, John O L DeLancey

Abstract read
In one paragraph

Article in International urogynecology journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Observational
  11. Article
  12. What's new in the functional anatomy of pelvic organ prolapse?Current opinion in obstetrics & gynecology · 2016
    Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aisha YousufDepartment of Obstetrics and Gynecology (Pelvic Floor Research Group), University of Michigan Hospital, Ann Arbor, MI, 48109, USA.
Luyun Chen
Kindra Larson
James A Ashton-Miller
John O L DeLancey

Funding

Which pelvic floor defects cause stress incontinence?P50HD044406 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DELANCEY, JOHN O.L. · 2002 to 2017
$17.1M
Michigan BIRCWH Career Development ProgramK12HD001438 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JOHNSON, TIMOTHY RB · 2000 to 2014
$6.7M
Mechanisms of anterior vaginal wall support failureR01HD038665 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DELANCEY, JOHN O.L. · 2000 to 2014
$3.8M
NICHD NIH HHS K12 HD001438NICHD NIH HHS K12 HD004438NICHD NIH HHS P50 HD044406NICHD NIH HHS R01 HD 038665NICHD NIH HHS R01 HD038665
6 · The paper itself

Abstract

introduction and hypothesisIn cystoceles, the distal anterior vaginal wall (AVW) bulges out through the introitus and is no longer in contact with the posterior vaginal wall or perineal body, exposing the pressure differential between intra-abdominal pressure and atmospheric pressure. The goal of this study is to quantify the length of the exposed vaginal wall length and to investigate its relationship with other factors associated with the AVW support, such as most dependent bladder location, apical location, and hiatus diameter, demonstrating its key role in cystocele formation.

methodsFifty women were selected to represent a full spectrum of AVW support. Each underwent supine, dynamic MR imaging. Most dependent bladder location and apical location were measured relative to the average normal position on the mid-sagittal plane using the Pelvic Inclination Correction System . The length of the exposed AVW and the hiatus diameter were measured as well. The relationship between exposed AVW and most dependent bladder location, apical location, and hiatus diameter were examined.

resultsA bilinear relationship has been observed between exposed vaginal wall length and most dependent bladder location (R(2) = 0.91, P < 0.001). When the bladder descents up to the inflection point (about 4.4 cm away from its normal position), there is little change in the exposed AVW length. With further descent, the exposed vaginal wall length increases significantly, with a 2 cm increase in exposed AVW length for every additional 1 cm of drop bladder location. A similar but weaker bilinear relationship exists between exposed AVW and apical location. Exposed vaginal wall length is also highly correlated with hiatus diameter (R(2) = 0.85, P < 0.001).

conclusionA bilinear relationship exists between exposed vaginal wall length and most dependent bladder location and apical location. It is when the bladder descent is beyond the inflection point that exposed vaginal wall length increases significantly.

Indexed as

Abdominal CavityAdultCase-Control StudiesCystoceleFemaleHumansMagnetic Resonance ImagingMiddle AgedPelvic FloorPressureUrinary BladderVaginaValsalva Maneuver

Identifiers

PMID24737299
PMCPMC4169320

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.