Evidence map›Paper›PMID 24736894›Full record

ArticleInternational journal of clinical pharmacy2014

Characterization of drug-related problems identified by clinical pharmacy staff at Danish hospitals.

Lene Juel Kjeldsen, Trine Birkholm, Hanne Fischer, Trine Graabæk, Karina Porsborg Kibsdal, Lene Vestergaard Ravn-Nielsen, Tania Holtum Truelshøj

Abstract readEvaluation StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in International journal of clinical pharmacy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
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  4. Identifying Drug-Therapy Problems among Syrian Refugees in Zaatari Refugee Camp.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Lene Juel KjeldsenThe Danish Research Unit for Hospital Pharmacy, Amgros I/S, Dampfærgevej 22, 2100, Copenhagen Ø, Denmark, ljk@amgros.dk.
Trine Birkholm
Hanne Fischer
Trine Graabæk
Karina Porsborg Kibsdal
Lene Vestergaard Ravn-Nielsen
Tania Holtum Truelshøj
Central Denmark Region · DKCopenhagen University Hospital · DKHospital South West Jutland · DKNorth Denmark Region · DKOdense University Hospital · DKRegion Zealand · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2010, a database of drug related problems (DRPs) was implemented to assist clinical pharmacy staff in documenting clinical pharmacy activities locally. A study of quality, reliability and generalisability showed that national analyses of the data could be conducted. Analyses at the national level may help identify and prevent DRPs by performing national interventions.

objectiveThe aim of the study was to explore the DRP characteristics as documented by clinical pharmacy staff at hospital pharmacies in the Danish DRP-database during a 3-year period.

settingDanish hospital pharmacies.

methodData documented in the DRP-database during the initial 3 years after implementation were analyzed retrospectively. The DRP-database contains DRPs reported at hospitals by clinical pharmacy staff. The analyses focused on DRP categories, implementation rates and drugs associated with the DRPs.

main outcome measureCharacteristics of DRPs.

resultsIn total, 72,044 DRPs were documented in the DRP-database during the first 3 years of implementation, and the number of documented DRPs increased every year. An overall stable implementation rate of approximately 58 % was identified. The DRPs identified were multi-facetted, however evenly distributed for each of the 3 years. The most frequently identified DRP categories were: "Dose", followed by "Nonadherence to guidelines" and "Supplement to treatment". The highest implementation rates were found for the following DRP categories: "Non-adherence to guidelines" (79 %) followed by "Therapeutic duplication" (73 %) and "Dosing time and interval" (70 %). Even though the top 25 drugs were involved in 58 % of all DRPs, multiple drugs were associated with DRPs. The drugs most frequently involved in DRPs were paracetamol (4.6 % of all DRPs), simvastatin (3.0 %), lansoprazole (2.7 %), morphine (2.6 %) and alendronic acid (2.4 %).

conclusionsThe study found that a national database on DRPs contained multi-facetted DRPs, however evenly distributed for each of the 3 years. Even though the top 25 drugs were involved in 58 % of all DRPs, multiple drugs were associated with DRPs. The study emphasizes the importance of detecting and intervening for DRPs.

Indexed as

Adverse Drug Reaction Reporting SystemsHealth Plan ImplementationMedication ReconciliationPharmacology, ClinicalPharmacy Service, HospitalQuality of Health CareDenmarkDrug MonitoringDrug Therapy, CombinationElectronic Health RecordsFollow-Up StudiesGuideline AdherenceHumansPractice Guidelines as TopicPractice Patterns, Physicians'Prescription DrugsPrescription Drugs

Identifiers

PMID24736894
OpenAlexW1986879875

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.