Evidence map›Paper›PMID 24735874›Full record

ArticleDevelopmental cell2014

Ovol proteins: guardians against EMT during epithelial differentiation.

Shan Li, Jing Yang

Abstract readComment
In one paragraph

Article in Developmental cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
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  5. Review
  6. Review
  7. Article
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  11. Potential role of the OVOL1-OVOL2 axis and c-Myc in the progression of cutaneous squamous cell carcinoma.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2017
    Article
  12. Article
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  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Shan LiDepartment of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA.
Jing YangDepartment of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: jingyang@ucsd.edu.

Funding

Regulation of Tumor Invasion by Twist1R01CA168689 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI YANG, JING · 2012 to 2016
$1.7M
NCI NIH HHS R01 CA168689
6 · The paper itself

Abstract

Epithelial differentiation requires a balancing act to commit to epithelial fate while inhibiting both progenitor and mesenchymal traits. In this issue of Developmental Cell, Lee et al. (2014) and Watanabe et al. (2014) uncover a critical role of Ovol proteins in safeguarding this intricate process.

Indexed as

Cell DifferentiationEpidermal CellsEpithelial-Mesenchymal TransitionGene Expression Regulation, DevelopmentalMorphogenesisRegenerationTranscription, GeneticAnimalsEmbryonic Stem CellsFemaleHumansMammary Glands, AnimalTranscription FactorsMOVO protein, mouseTranscription Factors

Identifiers

PMID24735874
PMCPMC4106710

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.