ArticleBMC plant biology2014
Transcriptome profiling of genes and pathways associated with arsenic toxicity and tolerance in Arabidopsis.
Article in BMC plant biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 110 citations in OpenAlex.
- Review
- Genomic Survey of Genes Encoding Major Intrinsic Proteins (MIPs) and Their Response to Arsenite Stress in Pepper (Plants (Basel, Switzerland) · 2025Article
- Genes to specialized metabolites: accumulation of scopoletin, umbelliferone and their glycosides in natural populations of Arabidopsis thaliana.BMC plant biology · 2024Article
- Plasma membrane-associated calcium signaling regulates arsenate tolerance in Arabidopsis.Plant physiology · 2023Article
- Transcriptome Analysis Reveals Differentially Expressed Genes Involved in Cadmium and Arsenic Accumulation in Tea Plant (Plants (Basel, Switzerland) · 2023Article
- Genome-wide association mapping and genomic prediction for late blight and potato cyst nematode resistance in potato (Frontiers in plant science · 2023Article
- The genetic basis of adaptation to copper pollution inFrontiers in genetics · 2023Article
- Endophytic yeast protect plants against metal toxicity by inhibiting plant metal uptake through an ethylene-dependent mechanism.Plant, cell & environment · 2023Article
- Molecular insight into arsenic uptake, transport, phytotoxicity, and defense responses in plants: a critical review.Planta · 2022Review
- Arsenic perception and signaling: The yet unexplored world.Frontiers in plant science · 2022Review
- The SLIM1 transcription factor is required for arsenic resistance in Arabidopsis thaliana.FEBS letters · 2021Article
- Metal and Metalloid Toxicity in Plants: An Overview on Molecular Aspects.Plants (Basel, Switzerland) · 2021Review
- Temperature Regulation of Primary and Secondary Seed Dormancy inInternational journal of molecular sciences · 2020Article
- Effect of Arsenic Stress on Expression Pattern of a Rice SpecificFrontiers in plant science · 2020Article
- Evolution of Abscisic Acid Signaling for Stress Responses to Toxic Metals and Metalloids.Frontiers in plant science · 2020Review
- QTL Analysis of Resistance to High-Intensity UV-B Irradiation in Soybean (International journal of molecular sciences · 2019Article
- HSFA2 Functions in the Physiological Adaptation of Undifferentiated Plant Cells to Spaceflight.International journal of molecular sciences · 2019Article
- Early transcriptional response pathways in Daphnia magna are coordinated in networks of crustacean-specific genes.Molecular ecology · 2018Article
- Traversing the Links between Heavy Metal Stress and Plant Signaling.Frontiers in plant science · 2018Review
- Transcriptional changes measured in rice roots after exposure to arsenite-contaminated sediments.Environmental science and pollution research international · 2018Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundArsenic (As) is a toxic metalloid found ubiquitously in the environment and widely considered an acute poison and carcinogen. However, the molecular mechanisms of the plant response to As and ensuing tolerance have not been extensively characterized. Here, we report on transcriptional changes with As treatment in two Arabidopsis accessions, Col-0 and Ws-2.
resultsThe root elongation rate was greater for Col-0 than Ws-2 with As exposure. Accumulation of As was lower in the more tolerant accession Col-0 than in Ws-2. We compared the effect of As exposure on genome-wide gene expression in the two accessions by comparative microarray assay. The genes related to heat response and oxidative stresses were common to both accessions, which indicates conserved As stress-associated responses for the two accessions. Most of the specific response genes encoded heat shock proteins, heat shock factors, ubiquitin and aquaporin transporters. Genes coding for ethylene-signalling components were enriched in As-tolerant Col-0 with As exposure. A tolerance-associated gene candidate encoding Leucine-Rich Repeat receptor-like kinase VIII (LRR-RLK VIII) was selected for functional characterization. Genetic loss-of-function analysis of the LRR-RLK VIII gene revealed altered As sensitivity and the metal accumulation in roots.
conclusionsThus, ethylene-related pathways, maintenance of protein structure and LRR-RLK VIII-mediated signalling may be important mechanisms for toxicity and tolerance to As in the species. Here, we provide a comprehensive survey of global transcriptional regulation for As and identify stress- and tolerance-associated genes responding to As.
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